Driven by a sufficiently powerful pump laser, a cavity optomechanical system will stabilize in coupled oscillations of its cavity field and mechanical resonator. It was assumed that the oscillation will be continuously magnified upon enhancing the driving laser further. However, based on the nonlinear dynamics of the system, we find that the dynamical behaviors of the system are much more complex than this intuitive picture, especially when it is operated near the blue detuning point by the mechanical resonator's intrinsic frequency. There exists an anomalous stabilization: depending on its intrinsic damping rate and the pump power, the mechanical resonator will metastably stay on one orbit of oscillation after another until it completely stabilizes on the final orbit it can reach. These orbits are consistent with the locked ones with almost fixed oscillation amplitudes, which are realized after the pump power becomes still higher. The oscillatory cavity field is seen to adjust its sidebands following the mechanical frequency shift due to optical spring effect, so that it always drives the mechanical resonator to near those locked orbits once the pump power is over a threshold. In the regimes with such correlation between cavity field sidebands and mechanical oscillation, the system's dynamical attractors are confined on the locked orbits and chaotic motion is also excluded.
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http://dx.doi.org/10.1103/PhysRevLett.133.103602 | DOI Listing |
Small
December 2024
Department of Chemical & Biomolecular Engineering, University of Notre Dame, Notre Dame, IN, 46556, USA.
Synthetic opioids, especially fentanyl and its analogs, have created an epidemic of abuse and significantly increased overdose deaths in the United States. Current detection methods have drawbacks in their sensitivity, scalability, and portability that limit field-based application to promote public health and safety. The need to detect trace amounts of fentanyl in complex mixtures with other drugs or interferents, and the continued emergence of new fentanyl analogs, further complicates detection.
View Article and Find Full Text PDFMicrobiome
December 2024
Section for Oral Ecology, Cariology, Department of Dentistry and Oral Health, Aarhus University, Vennelyst Boulevard 9, 8000, Aarhus C, Denmark.
Background: Correlative structural and chemical imaging of biofilms allows for the combined analysis of microbial identity and metabolism at the microscale. Here, we developed pH-FISH, a method that combines pH ratiometry with fluorescence in situ hybridization (FISH) in structurally intact biofilms for the coupled investigation of microbial acid metabolism and biofilm composition. Careful biofilm handling and modified sample preparation procedures for FISH allowed preservation of the three-dimensional biofilm structure throughout all processing and imaging steps.
View Article and Find Full Text PDFJ Appl Clin Med Phys
December 2024
Department of Radiation Oncology, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida, Boca Raton, Florida, USA.
Purpose: A novel proton beam delivery method known as DynamicARC spot scanning has been introduced. The current study aims to determine whether the partial proton arc technique, in conjunction with DynamicARC pencil beam scanning (PBS), can meet clinical acceptance criteria for bilateral head and neck cancer (HNC) and provide an alternative to full proton arc and traditional intensity-modulated proton therapy (IMPT).
Method: The study retrospectively included anonymized CT datasets from ten patients with bilateral HNC, all of whom had previously received photon treatment.
ACS Macro Lett
December 2024
Department of Gynaecology and Obstetrics, Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center for Anesthesiology and Perioperative Medicine Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People's Hospital School of Medicine, Tongji University, Shanghai 200434, China.
Nanobowls show promising potential in biomedical applications, such as bioimaging, cargo delivery, and disease theranostics, due to their unique concave structure and interior cavities. However, the lack of biodegradable nanobowls with manipulable size (especially the dent size) still exists as an obstacle for their in-depth exploration and application in biomedical fields. Herein, polypeptide-based nanobowls are successfully obtained by the self-assembly of a graft polypeptide [named TPE-P(GAAzo--GA)] via a solvent-switch method.
View Article and Find Full Text PDFBMC Musculoskelet Disord
December 2024
Department of Physiotherapy, University of Málaga, The Institute of Biomedical Research in Málaga (IBIMA), Clinimetric Group FE-14, Málaga, Spain.
Background: Glenohumeral instability is a highly prevalent pathology; however, there are problems in defining it. Traditionally, structural problems such as labral injury or bone loss in the glenoid cavity and/or humeral side were considered the main causes; but recently, it has been seen that motor control plays a very relevant role. This means that currently, there is a disparity of action protocols, and the treatment of this pathology is a great challenge.
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