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Viral Infection in Endometritis: Is There an Important Role or Not? | LitMetric

Viral Infection in Endometritis: Is There an Important Role or Not?

Am J Reprod Immunol

Infectious Diseases Research Center, Health Research Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Published: September 2024

AI Article Synopsis

  • Chronic endometritis (CE) is a common condition characterized by inflammation in the endometrium that can negatively impact fertility, contributing to issues like recurrent miscarriage and implantation failure.
  • This review explores the connection between viral infections and CE, suggesting that these infections might alter the endometrial environment and play a significant role in infertility.
  • The review aims to be the first of its kind to specifically highlight how viral infections could be a potential cause of chronic endometritis and their potential implications for fertility.

Article Abstract

Chronic endometritis (CE) is a frequent pathological condition that is defined as localized inflammation in the endometrium. Some adverse fertility consequences such as recurrent miscarriage and failure of implantation are associated with chronic endometritis. On the one hand, inflammation plays an important role in the pathogenesis of endometritis, and on the other hand, the role of viral infections in inducing inflammation can make this review strongly attractive and practical. We set out to provide an overview of viral infections as a potential etiology of CE pathophysiology through the alteration of an endometrial microenvironment and its association with infertility. To the best of our knowledge, this is the first review to demonstrate the role of viral infection in chronic endometritis, and whether or not infection ultimately plays a role..

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Source
http://dx.doi.org/10.1111/aji.13930DOI Listing

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