AI Article Synopsis
- Human herpesvirus 6 (HHV-6) often causes roseola infantum in children but can rarely lead to encephalitis, especially in immunocompromised individuals due to reactivation.
- This review focuses on cases of HHV-6 encephalitis in immunocompetent adults, analyzing the varying diagnostic approaches and treatment strategies used.
- The study emphasizes the need for clearer diagnostic guidelines for HHV-6 encephalitis in healthy adults, suggesting certain diagnostic methods that could improve the understanding and management of this rare condition.
Article Abstract
Human herpesvirus 6 (HHV-6) is associated with its presentation in the pediatric population as roseola infantum. Rarely, it is the causative agent of encephalitis, with most cases reported among the immunocompromised population due to reactivation. This review article analyzes the published records of cases labeled HHV-6 encephalitis in immunocompetent adults, aiming to understand the diagnostic methods behind each case and explore the complexities of such a diagnosis. We note significant variability in the methods used to come to a diagnosis of HHV-6 encephalitis, as well as inconsistent approaches to treatment of this condition. Given the rarity of HHV-6 encephalitis in immunocompetent adults, there are no clearly structured diagnostic guidelines for this condition in this patient population. We highlight several diagnostic methods that provide more convincing evidence of true HHV-6 encephalitis and may provide a basis for further development of guidelines for the diagnosis and treatment of this condition.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11412321 | PMC |
| http://dx.doi.org/10.1093/ofid/ofae501 | DOI Listing |
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