The goal of Partial Domain Adaptation (PDA) is to transfer a neural network from a source domain (joint source distribution) to a distinct target domain (joint target distribution), where the source label space subsumes the target label space. To address the PDA problem, existing works have proposed to learn the marginal source weights to match the weighted marginal source distribution to the marginal target distribution. However, this is sub-optimal, since the neural network's target performance is concerned with the joint distribution disparity, not the marginal distribution disparity. In this paper, we propose a Joint Weight Optimization (JWO) approach that optimizes the joint source weights to match the weighted joint source distribution to the joint target distribution in the neural network's feature space. To measure the joint distribution disparity, we exploit two statistical distances: the distribution-difference-based L-distance and the distribution-ratio-based χ-divergence. Since these two distances are unknown in practice, we propose a Kernel Statistical Distance Estimation (KSDE) method to estimate them from the weighted source data and the target data. Our KSDE method explicitly expresses the two estimated statistical distances as functions of the joint source weights. Therefore, we can optimize the joint weights to minimize the estimated distance functions and reduce the joint distribution disparity. Finally, we achieve the PDA goal by training the neural network on the weighted source data. Experiments on several popular datasets are conducted to demonstrate the effectiveness of our approach. Intro video and Pytorch code are available at https://github.com/sentaochen/Joint-Weight-Optimation. Interested readers can also visit https://github.com/sentaochen for more source codes of the related domain adaptation, multi-source domain adaptation, and domain generalization approaches.
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http://dx.doi.org/10.1016/j.neunet.2024.106739 | DOI Listing |
Immunol Rev
December 2024
Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
αβT cells protect vertebrates against many diseases, optimizing surveillance using mechanical force to distinguish between pathophysiologic cellular alterations and normal self-constituents. The multi-subunit αβT-cell receptor (TCR) operates outside of thermal equilibrium, harvesting energy via physical forces generated by T-cell motility and actin-myosin machinery. When a peptide-bound major histocompatibility complex molecule (pMHC) on an antigen presenting cell is ligated, the αβTCR on the T cell leverages force to form a catch bond, prolonging bond lifetime, and enhancing antigen discrimination.
View Article and Find Full Text PDFPlant Cell Environ
January 2025
Key Laboratory of the State Forestry and Grassland Administration for the Cultivation of Forests in the Lower Reaches of the Yellow River, College of Forestry, Shandong Agricultural University, Tai'an, China.
How different stress responses by male and female plants are influenced by interactions with rhizosphere microbes remains unclear. In this study, we employed poplar as a dioecious model plant and quantified biotic associations between microorganisms to explore the relationship between microbial associations and plant adaptation. We propose a health index (HI) to comprehensively characterize the physiological characteristics and adaptive capacity of plants under stress.
View Article and Find Full Text PDFThe risk of severe outcomes of influenza increases during pregnancy. Whether vaccine-induced T cell memory-primed prepregnancy retains the ability to mediate protection during pregnancy, when systemic levels of several hormones with putative immunomodulatory functions are increased, is unknown. Here, using murine adoptive transfer systems and a translationally relevant model of cold-adapted live-attenuated influenza A virus vaccination, we show that preexisting virus-specific memory T cell responses are largely unaltered and highly protective against heterotypic viral challenges during pregnancy.
View Article and Find Full Text PDFAm J Occup Ther
January 2025
Henry C. Hrdlicka, PhD, is Director of Research, Milne Institute for Healthcare Innovation, Gaylord Specialty Healthcare, Wallingford, CT;
Importance: No single cognitive screen adequately captures the cognitive domains needed for inpatient occupational therapy treatment planning.
Objective: To assess the construct validity of the Gaylord Occupational Therapy Cognitive (GOT-Cog©) screen, a novel comprehensive cognitive screen that evaluates functional cognition.
Design: Randomized crossover controlled study design using the St.
Public Health Nutr
January 2025
Universite Joseph KI ZERBO, Burkina Faso.
Objective: The creation of a healthy food environment is highly dependent on the policies that governments choose to implement. The objective of this study is to compare the level of implementation of current public policies aimed at creating healthy food environments in Burkina Faso with international good practice indicators.
Design: This evaluation was carried out using the Food-EPI tool.
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