Purpose: To explore the therapeutic effects of orthokeratology lens combined with 0.01% atropine eye drops on juvenile myopia.
Methods: A total of 340 patients with juvenile myopia (340 eyes) treated from 2018 to December 2020 were divided into the control group (170 cases with 170 eyes, orthokeratology lens) and observation group (170 cases with 170 eyes, orthokeratology lens combined with 0.01% atropine eye drops). The best-corrected distance visual acuity, best-corrected near visual acuity, diopter, axial length, amplitude of accommodation, bright pupil diameter, dark pupil diameter, tear-film lipid layer thickness, and tear break-up time were measured before treatment and after 1 year of treatment. The incidence of adverse reactions was observed.
Results: Compared with the values before treatment, the spherical equivalent degree was significantly improved by 0.22 (0.06, 0.55) D and 0.40 (0.15, 0.72) D in the observation and control groups after the treatment, respectively (p<0.01). After the treatment, the axial length was significantly increased by (0.15 ± 0.12) mm and (0.24 ± 0.11) mm in the observation and control groups, respectively, (p<0.01). After the treatment, the amplitude of accommodation significantly declined in the observation group and was lower than that in the control group, whereas both bright and dark pupil diameters significantly increase and were larger than those in the control group (p<0.01). After the treatment, the tear-film lipid layer thickness and tear break-up time significantly declined in the two groups (p<0.01).
Conclusions: Orthokeratology lens combined with 0.01% atropine eye drops can synergistically enhance the control effect on juvenile myopia with high safety.
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http://dx.doi.org/10.5935/0004-2749.2022-0247 | DOI Listing |
Adv Exp Med Biol
January 2025
Department of Optometry, University of Benin, Benin City, Nigeria.
Contact lenses have become integral tools in the realm of ocular therapeutics, extending beyond their primary function of refractive correction to encompass a diverse array of therapeutic applications. This review explores the evolving role of contact lenses in managing various ocular conditions, highlighting their efficacy in enhancing patient outcomes. Initially developed to correct refractive errors, contact lenses now serve as effective vehicles for delivering medications directly to the ocular surface, offering targeted treatment for conditions such as dry eye syndrome and corneal ulcers.
View Article and Find Full Text PDFClin Exp Optom
January 2025
Aier Eye Hospital, Jinan University, Guangzhou, China.
Clinical Relevance: When selecting an intervention for myopia management, parental inquiries centre around the comparative efficacy of orthokeratology versus myopic defocus spectacle lenses. This prompts an intriguing investigation into the nuanced differences between these two treatment methods.
Background: This study aimed to compare the efficacy of spectacle lenses with highly aspherical lenslets (HAL) versus orthokeratology (Ortho-k) in controlling axial length elongation.
Cont Lens Anterior Eye
January 2025
State Key Laboratory of Ophthalmology, Optometry and Vision Science, Eye Hospital, Wenzhou Medical University, Wenzhou, China; National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital Wenzhou Medical University, Wenzhou, China. Electronic address:
Purpose: To compare the two-year efficacy of spectacle lenses with highly aspherical lenslets (HAL) and orthokeratology (OK) lenses in managing myopia in children.
Methods: This retrospective study examined medical records from the Affiliated Eye Hospital of Wenzhou Medical University, involving 1683 HAL users and 1192 OK users. Participants were children aged 8-13 with a refractive error of -0.
Clin Exp Optom
January 2025
Eurolens Research, Division of Pharmacy and Optometry, The University of Manchester, Manchester, UK.
Clinical Relevance: Knowledge of contact lens prescribing trends can (a) assist practitioners to benchmark their own prescribing habits, (b) help the contact lens industry understand preferred products, and (c) support academics in scholarly writings.
Background: This work aims to document contact lens prescribing trends in Australia over the past quarter of a century.
Methods: An annual survey of contact lens prescribing trends was conducted in Australia each year from 2000 to 2024, inclusive, by asking optometrists to provide information relating to 10 consecutive contact lens fits undertaken between January and March.
Am J Ophthalmol
January 2025
Department of Ophthalmology, University of Warmia and Mazury, Olsztyn, Poland; Institute for Research in Ophthalmology, Foundation for Ophthalmology Development, Poznan Poland. Electronic address:
Purpose: Treatment of myopia has been informed by more than 3 decades of clinical trials and other observations. However, controversies regarding myopia control remain, such as when to stop treatment and what is the long-term efficacy of treatment. This perspective aims to describe clinically relevant and current controversies regarding myopia treatment.
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