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Deciphering community-level knowledge of obstetric fistula and determinants: perspectives elucidated by ordinal logistic regression.
Front Glob Womens Health
December 2024
United Nation Population Fund Supported Maternal Project, University of Gondar, Gondar, Ethiopia.
Background: Obstetric fistula is a significant cause of maternal morbidity in resource-limited settings, where women often suffer due to a lack of prompt access to skilled obstetric services. It is imperative to comprehend and identify the factors that shape community knowledge about obstetric fistula to enhance prevention strategies, enable early detection, and provide support and treatment to affected women. However, there is a substantial gap in the available evidence concerning the level of community knowledge regarding obstetric fistula and its influencing factors within the Ethiopian context.
View Article and Find Full Text PDFMFSD2A Overexpression Inhibits Hepatocellular Carcinoma Through TGF-β/Smad Signaling.
Mol Carcinog
January 2025
Department of Hepatobiliary Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Hepatocellular carcinoma (HCC) is a common primary malignancy of the liver and has a high mortality. Major facilitator superfamily domain containing 2 (MFSD2A) was previously demonstrated to inhibit tumor progression in several cancers. Here, we elucidated the association between MFSD2A expression and HCC progression and also investigated the underlying mechanism.
View Article and Find Full Text PDFChronic Kidney Disease Prevalence in India: A Systematic Review and Meta-Analysis From Community-Based Representative Evidence Between 2011 to 2023.
Nephrology (Carlton)
January 2025
Jawaharlal Institute of Post Graduate Medical Education and Research, Puducherry, India.
Chronic kidney disease (CKD) prevalence varies widely across different regions of India. We aimed to identify the status of CKD in India, by systematically reviewing the published community-based studies between the period of January 2011 to December 2023. PubMed, Scopus, and EMBASE were searched for peer-reviewed evidence.
View Article and Find Full Text PDFFerric carboxymaltose for anemia in late pregnancy: a randomized controlled trial.
Nat Med
January 2025
Training and Research Unit of Excellence (TRUE), Blantyre, Malawi.
Over 46% of African pregnant women are anemic. Oral iron is recommended but often suboptimal, particularly late in pregnancy. Intravenous ferric carboxymaltose (FCM) could treat anemia in women in the third trimester in sub-Saharan Africa.
View Article and Find Full Text PDFInfants of diabetic mothers: epidemiology, pathophysiology, fetal heartassessment, structural and functional heart consequences: A narrative review.
Cardiol Young
January 2025
Department of Community Medicine, F.H. Medical College, Agra, Uttar Pradesh, India.
Infants of diabetic mothers are neonates born to a woman who had periodic hyperglycaemia during pregnancy. Consequently, infants of diabetic mothers are at higher risks of illness besides morbidity and mortality due to teratogenic effects on the fetal cardiovascular system, causing most frequent CHDs. The primary purpose of this review is to present, on this topic, a better-comprehended review covering pertinent material and data to be informed of severe risks to a newborn's cardiac system and function.
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