A novel and unique approach for the construction of polysubstituted pyrimido[4,5-]indoles from 2-(indol-3-yl)naphthoquinones and benzamidines is described. Our strategy, promoted by an inorganic base, involves the ring opening and recyclization of naphthoquinone and produces three nitrogen heterocyclic rings via multiple C-N bond formations in one pot under transition-metal-free conditions.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.orglett.4c02847 | DOI Listing |
Publication Analysis
Top Keywords
2-indol-3-ylnaphthoquinones benzamidines
8
polysubstituted pyrimido[45-]indoles
8
base-promoted tandem
4
tandem cyclization
4
cyclization 2-indol-3-ylnaphthoquinones
4
benzamidines polysubstituted
4
pyrimido[45-]indoles novel
4
novel unique
4
unique approach
4
approach construction
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!