A Current Perspective on the Effects of Flavonoids in the Treatment of Acne.

Infect Disord Drug Targets

Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, 203201, India.

Published: September 2024

AI Article Synopsis

  • Acne, including pimples and blackheads, is caused by the blockage of hair follicles by dead skin cells and oils, and can affect anyone at any age, though it's most common in teenagers.
  • The inflammation that characterizes acne can leave behind scars and marks even after the breakouts heal.
  • This study explores six types of flavonoids found in plants that may help treat acne and discusses the molecular docking results of proteins related to acne treatment.

Article Abstract

Pimples, blackheads, whiteheads, etc., are common types of acne that pop up on the skin each time, whenever dead cells and oils obstruct the outgrowth of hair from the hair follicle. It is very common to observe this condition in teenagers, but regardless of age, if the causing condition is met, acne can occur at any point in life. The characteristic feature of all types of acne is it starts with inflammation of the skin. These inflammatory marks (like black spots, pores, small scars, etc.) leave behind even when acne disappears. Plants like vegetables and flowers are naturally rich in different types of polyphenolic compounds called flavonoids. These flavonoids have various key functions, from guiding cell movement to maintaining oxidative pressure in the body. In this study, we discuss six types of flavonoids that have the potential to be used as med-icine for the treatment of different kinds of skin breakouts. Moreover, the result of molecular docking of different proteins that have an association with acne is also discussed.

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Source
http://dx.doi.org/10.2174/0118715265299763240818161040DOI Listing

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