Resveratrol as well as natural products biosynthetically derived from it, have been shown to have protective effects against oxidative stress. However, these compounds possess poor druglike properties. At sub-nanomolar concentrations, a novel compound (RVM-6) inspired by a resveratrol natural product prolongs synaptic viability in neuromuscular junctions in exposed to acute oxidative stress.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11409061 | PMC |
http://dx.doi.org/10.17912/micropub.biology.001127 | DOI Listing |
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