Resveratrol as well as natural products biosynthetically derived from it, have been shown to have protective effects against oxidative stress. However, these compounds possess poor druglike properties. At sub-nanomolar concentrations, a novel compound (RVM-6) inspired by a resveratrol natural product prolongs synaptic viability in neuromuscular junctions in exposed to acute oxidative stress.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11409061PMC
http://dx.doi.org/10.17912/micropub.biology.001127DOI Listing

Publication Analysis

Top Keywords

oxidative stress
12
resveratrol natural
8
natural product
8
acute oxidative
8
product inspired
4
inspired compound
4
compound potent
4
potent neuroprotectant
4
neuroprotectant acute
4
stress resveratrol
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!