AI Article Synopsis
- A study analyzed the clinical characteristics of 234 patients with nontuberculous mycobacterium (NTM) pulmonary disease in Fuyang, China, from January 2018 to May 2023.
- It found that over 31% of patients had a history of tuberculosis (TB) and bronchiectasis, with certain NTM strains more common in this group.
- The research concluded that previous TB exposure significantly increases the risk of developing NTM disease, and the most prevalent strains in the region were identified, although the symptoms were not specific to any one species.
Article Abstract
Objective: We retrospectively review consecutive patients with nontuberculous mycobacterium (NTM) pulmonary disease reported from a designated hospital for infectious diseases in the Fuyang district of China to determine the clinical characteristics of these patients.
Methods: This research enrolled 234 patients with NTM pulmonary disease between January 2018 and May 2023 in the Fuyang district of China. Data were collected from the electronic medical records. The NTM strain composition and clinical characteristics of NTM pulmonary disease were retrospectively analyzed.
Results: 73 (31.20%) patients had previous tuberculosis (TB) or TB exposure history and bronchiectasis. Mixed NTM infection accounted for 12.39%. strain was detected in 132 patients (49.62%). Women were found to be more affected by infection, and men by infection. (34.21%) and (33.33%) strains were most common in people with previous TB or TB exposure history. Among respiratory tract-related diseases, patients with bronchiectasis had the highest isolation rate of (55.36%). Women were susceptible to bronchiectasis ( <0.01). The median of mononuclear-to-lymphocyte ratio (MLR) was higher in men than in women (P < 0.01). The serum albumin (ALB) level was lower in patients with TB or TB exposure history than in those without TB history ( = 0.034). The prognostic nutritional index (PNI) was lower in patients with TB or TB exposure history than in those without tuberculosis history ( = 0.021). Patients with NTM lung disease were poorly treated.
Conclusion: Clinical symptoms of the disease were not species-specific. and strains were predominant in the Fuyang district of China. Previous TB or TB exposure history immensely enhanced the risk of NTM disease.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11410028 | PMC |
| http://dx.doi.org/10.2147/IDR.S475652 | DOI Listing |
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