Many events in power networks which caused failure and outage of subsystems have root in design and initial selection of equipment and their specification. This concern will be important while the any kind of expanding and acclimation plan need to be executed to strengthen the existing infrastructures in order to provide better condition with regard to satisfied criteria. In Iran one of the most adverse environmental occurrences known Fine Dust, may force several distribution utilities to be changed due to new technical requirements. Medium voltage level regrading in way to decrease or unification of distribution system have been proposed in this paper to reach reduced faults and fast replacement of equipment in damaged situations. Voltage level changing and selection have been investigated in order to increase the network strengthen and reselection of equipment and redesigning critical sections of system against natural events that called fine dust with aim to attain an upgraded distribution utility. Operating of existing 33 kV and 11 kV network in 20 kV level and investigation of changing process have been done for Ahvaz medium voltage distribution system as a case study in these paper's sections. Calculations and results will be contained maximum current capacities in different line conductors, insulation and air clearances assessment, poles acceptable mechanical values, short circuit current and protection coordination for changing voltage level in distribution system.
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http://dx.doi.org/10.1016/j.heliyon.2024.e37335 | DOI Listing |
Int J Immunogenet
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Department of Clinical Haematology and Medical Oncology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
High degree of variability in human leukocyte antigens (HLAs) system restricts availability of histocompatible HLA-matched-related donors, thus increasing reliance on worldwide bone marrow registries network. Nevertheless, due to limited coverage/accessibility/affordability of some ethnicities in these registries, haploidentical haematopoietic stem cell transplantation (HSCT) emerged as an alternative option, though with allorecognition-mediated graft versus host disease (GvHD) (>40% cases). A dimorphism [-21 methionine (M) or threonine (T)] in HLA-B leader peptide (exon 1) which differentially influences its HLA-E binding, plausibly regulates natural killer cell functionality, affecting GvHD vulnerability and clinically in practice for donor selection.
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State Key Laboratory of Biocontrol, School of Marine Sciences, Sun Yat-sen University, Guangzhou, China.
Global warming has threatened all-rounded hierarchical biosphere by reconstructing eco-structure and bringing biodiversity variations. Pacific white shrimp, a successful model of worldwide utilizing marine ectothermic resources, is facing huge losses due to multiple diseases relevant to intestinal microbiota (IM) dysbiosis during temperature fluctuation. However, how warming mediates shrimp health remains poorly understood.
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January 2025
Institute of Life Course and Medical Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.
Low-density lipoprotein receptor-related protein 1 (LRP1) is a multifunctional endocytic receptor whose dysfunction is linked to developmental dysplasia of the hip, osteoporosis and osteoarthritis. Our work addresses the critical question of how these skeletal pathologies emerge. Here, we show the abundant expression of LRP1 in skeletal progenitor cells at mouse embryonic stage E10.
View Article and Find Full Text PDFNat Commun
January 2025
Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
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View Article and Find Full Text PDFVitam Horm
January 2025
Centro de Estudios Biomédicos Básicos, Aplicados y Desarrollo (CEBBAD), Universidad Maimónides, Ciudad Autónoma de Buenos Aires, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Ciudad Autónoma de Buenos Aires, Argentina. Electronic address:
Kisspeptin (KISS1), originally catalogued as metastin because of its capacity as a metastasis suppressor in human melanoma and breast cancer, is now recognized as the major puberty gatekeeper and gonadotropin-releasing hormone (GnRH) neuroendocrine system modulator. It is a member of the family of RFamide-related peptides that also includes the neuropeptide FF group, the gonadotropin-inhibitory hormone, the prolactin-releasing peptide, and the 26RFa peptides. The KISS1 precursor peptide is processed into a family of peptides known as kisspeptins.
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