Background: Magnetic resonance imaging (MRI) of the head and neck region is notably challenging due to the complex anatomy and the critical need for high-resolution imaging to accurately diagnose various pathologies. The two prominent MRI techniques used in this context are turbo spin echo (TSE) and echo-planar diffusion-weighted imaging (EP-DWI). TSE is recognized for providing high-resolution anatomical images, whereas EP-DWI offers functional imaging that highlights the diffusion of water molecules, essential for detecting early pathological changes. This study aims to compare the image quality of TSE and EP-DWI in the head and neck region to assess their diagnostic efficacy and clinical utility.
Methods: This retrospective study was conducted at Saveetha Medical College and Hospital over six months. A total of 100 patients (50 males and 50 females, aged 18-65 years) with various head and neck pathologies were included. Patients underwent both TSE and EP-DWI sequences using a Philips MULTIVA 1.5 T scanner. Image quality was assessed based on signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), artifact presence, and lesion detection. Two experienced radiologists independently reviewed the images, with inter-observer agreement calculated using Cohen's kappa coefficient.
Results: The mean SNR for TSE was significantly higher than EP-DWI (45.2 vs. 28.7, p<0.01), indicating superior image clarity and detail in TSE images. TSE demonstrated a higher mean CNR compared to EP-DWI (25.4 vs. 15.8, p<0.01), suggesting better differentiation between different tissue types and pathologies. Artifacts were more frequent in EP-DWI images (45% vs. 15%), with motion artifacts being the most common. TSE detected more lesions (120 vs. 95), with more precise delineation of lesions. The inter-observer agreement was excellent for both TSE and EP-DWI, with kappa values of 0.85 and 0.80, respectively.
Conclusion: TSE MRI provides superior image quality compared to EP-DWI for evaluating the head and neck region. The enhanced SNR and CNR in TSE images result in clearer and more detailed visualizations of anatomical structures and pathological changes, with fewer artifacts. While EP-DWI is valuable for functional imaging, its role should be complementary to TSE. The study suggests that TSE should be the preferred modality for detailed anatomical assessment in the head and neck region. Further studies with larger sample sizes and advanced imaging techniques may provide additional insights into optimizing MRI protocols for head and neck imaging.
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http://dx.doi.org/10.7759/cureus.67157 | DOI Listing |
Genome Med
January 2025
Otology & Neurotology Group CTS495, Instituto de Investigación Biosanitario, Ibs.GRANADA, Universidad de Granada, 18071, Granada, Spain.
Background: Familial Meniere's disease (FMD) is a rare polygenic disorder of the inner ear. Mutations in the connexin gene family, which encodes gap junction proteins, can also cause hearing loss, but their role in FMD is largely unknown.
Methods: We retrieved exome sequencing data from 94 individuals in 70 Meniere's disease (MD) families.
Diagn Pathol
January 2025
Department of Diagnostic Pathology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Background: Perivascular epithelioid cell tumors (PEComas) rarely appear in the head and neck region. This case report describes two transcription factor E3 (TFE3)-rearranged PEComa cases, consisting of one in the orbit and one in the nasal cavity.
Case Presentation: Both cases demonstrated sheet-like or focal nested architecture and comprised epithelioid cells with abundant clear to eosinophilic cytoplasm and vascular stroma.
BMC Cancer
January 2025
Department of Otorhinolaryngology, Shenzhen Key Laboratory of Otorhinolaryngology, Longgang Otorhinolaryngology Hospital, Shenzhen Institute of Otorhinolaryngology, No. 3004 Longgang Avenue, Shenzhen, Guangdong, China.
Background: To investigate the role of the translocase of the outer mitochondrial membrane 40 (TOM40) in oral squamous cell carcinoma (OSCC) with the aim of identifying new biomarkers or potential therapeutic targets.
Methods: TOM40 expression level in OSCC was evaluated using datasets downloaded from The Cancer Genome Atlas (TCGA), as well as clinical data. The correlation between TOM40 expression level and the clinicopathological parameters and survival were analyzed in TCGA.
Psychooncology
January 2025
School of Nursing, Hunan Normal University, Changsha, China.
Background: Postoperative patients with oral cancer are deeply distressed about their body image. However, their true inner feelings and the factors influencing body image remain unclear.
Aims: This study aims to investigate the experience of body image disturbance in patients 3 months after oral cancer surgery and analyze the influencing factors.
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