AI Article Synopsis
- Penile calciphylaxis is a rare but serious condition seen in patients with end-stage renal disease (ESRD), particularly those on dialysis.
- A 50-year-old man with a history of hypertension, diabetes, and ESRD experienced severe penile pain and was diagnosed after a circumcision revealed necrotic tissue.
- Despite treatment efforts, his condition progressed to gangrene, leading to a partial penectomy, highlighting the need for awareness of calciphylaxis in ESRD patients with penile symptoms.
Article Abstract
Penile calciphylaxis is a rare and severe complication primarily observed in patients with end-stage renal disease (ESRD) undergoing dialysis. A 50-year-old man presented with severe penile pain and phimosis. He had a history of hypertension and diabetes mellitus for 10 years, complicated by ESRD and was awaiting a cadaveric kidney transplant. He was on cinacalcet therapy for tertiary hyperparathyroidism. The patient underwent circumcision at which discolouration and necrotic patches involving the glans penis were noted. The histological findings were consistent with calciphylaxis and suppurative inflammation. However, due to persistent severe pain and progressive gangrene, a partial penectomy was performed. This report demonstrates the importance of consideration of calciphylaxis in patients with ESRD when presenting with penile pain, even phimosis.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11408742 | PMC |
| http://dx.doi.org/10.7759/cureus.67156 | DOI Listing |
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