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Case Report: A Case of Sporotrichoid Cutaneous Leishmaniasis Caused by Leishmania (Viannia) peruviana. | LitMetric

Case Report: A Case of Sporotrichoid Cutaneous Leishmaniasis Caused by Leishmania (Viannia) peruviana.

Am J Trop Med Hyg

Division of Medical Zoology, Department of Infection and Immunity, School of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan.

Published: November 2024

AI Article Synopsis

  • Leishmaniasis is an infection caused by protozoa from the Leishmania genus, leading to various clinical forms including cutaneous and visceral types.
  • Sporotrichoid cutaneous leishmaniasis (SCL) is a rare variation of cutaneous leishmaniasis primarily found in the Old World.
  • A case report details a Japanese man in Peru infected with Leishmania (Viannia) peruviana; his lesions spread from one foot to the lymph nodes, and resolved with treatment using intravenous liposomal amphotericin B, marking the first recorded case of SCL from this specific pathogen.

Article Abstract

Leishmaniasis is caused by an obligate intracellular protozoa of the genus Leishmania. Its clinical manifestations include cutaneous, mucocutaneous, and visceral forms. Sporotrichoid cutaneous leishmaniasis (SCL) is an atypical and rare form of cutaneous leishmaniasis (CL) reported mainly in the Old World. This case report describes SCL in a Japanese man infected with Leishmania (Viannia) peruviana in Peru. His lesions occurred on both feet, with the left foot lesion being a simple CL that resolved spontaneously. However, the lesion on the right foot did not cure by itself; instead, it progressed centrally along the lymph nodes, eventually forming an SCL. Amastigotes were detected in both feet and genetically identified as L. (V.) peruviana. The lesions gradually resolved after treatment with intravenous liposomal amphotericin B. Here, we report the first case of SCL caused by L. (V.) peruviana.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11542530PMC
http://dx.doi.org/10.4269/ajtmh.24-0275DOI Listing

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