AI Article Synopsis
- * Laboratory tests indicated he had acute kidney injury (AKI) along with low sodium, calcium, and potassium levels.
- * A kidney biopsy showed significant damage and a genetic test confirmed Bartter syndrome, leading to treatment with IV hydration and supplements, resulting in recovery from AKI.
Article Abstract
A 5-year-old male child with complaints of failure to thrive (since 4 months of age) and developmental delay presented to the nephrology department with complaints of weakness in all four limbs for 5 days. On examination, he was hypotensive, dehydrated, and had reduced tone in all four limbs. Biochemistry revealed acute kidney injury (AKI), hyponatremia, hypocalcemia, and hypokalemia. Renal needle biopsy (in view of unexplained AKI) revealed ropy, granular pigment casts with marked tubular injury. Myoglobin stain was positive. The positive genetic analysis of the patient (CLCNKB gene) confirmed the clinical diagnosis of Bartter syndrome (BS). The child was managed with aggressive intravenous hydration with potassium and calcium supplementation, and AKI recovered.
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| http://dx.doi.org/10.59556/japi.72.0653 | DOI Listing |
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