Introduction: Tinnitus is a common phenomenon with an estimated prevalence of 14.4% in the adult population. The experienced severity of tinnitus varies significantly among this population. Psychological factors have been identified as major contributors to this perceived severity, and numerous studies have demonstrated a correlation between symptoms of depression and tinnitus severity. However, the assessment of tinnitus severity and depressive symptoms often relies on self-report questionnaires, which show content overlap. This can pose challenges in distinguishing both conditions and interpreting their relationship. To address these challenges, the proposed study aims to examine the overlap between tinnitus and depressive symptom questionnaires by analyzing their content based on the International Classification of Functioning, Disability and Health (ICF) framework.
Methods And Analysis: Six validated, multi-item, self-report questionnaires measuring perceived tinnitus severity (THI, TQ, mTQ, THQ, TRQ, TFI) and seven validated, multi-item, self-report, depressive symptom questionnaires (BDI-II, HADS-D, SDS, PHQ-9, CES-D, SCL-90-R depression subscale, DASS-42 depression subscale) will be included in the content analysis. The content of all items of these questionnaires will be linked to ICF categories and item overlap between the tinnitus and depressive symptom questionnaires will be analyzed.
Discussion: By exploring the overlap between depression and tinnitus questionnaires, this study seeks to gain a better understanding of the relationship between tinnitus and depression, by distinguishing between shared content and independent constructs of symptom scores and shedding light on the factors influencing their measured severity.
Ethics And Dissemination: Ethical approval is not required for this study, due to the characteristics of the study design. Findings will be disseminated through peer-reviewed open access publication and scientific conferences.
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http://dx.doi.org/10.3389/fneur.2024.1376826 | DOI Listing |
PLoS One
December 2024
Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Subjective tinnitus is a phantom auditory perception in the absence of an actual acoustic stimulus that affects 15% of the global population. In humans, tinnitus is often associated with disturbed sleep and, interestingly, there is an overlap between the brain areas involved in tinnitus and regulation of NREM sleep. We used eight adult ferrets exposed to mild noise trauma as an animal model of tinnitus.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
December 2024
Neurosurgeon, MGIMS, Wardha, India.
We describe a case of a 24 year old female who came with complaint of bilateral tinnitus, profound hearing loss, and weakness in both lower limbs which on imaging work up showed unilateral acoustic schwannoma, and spinal extramedullary intradural lesions at D8-D9 level giving the classical features of neurofibromatosis II along with cafe au lait spots, axillary freckling, cutaneous neurofibromas, which are unique to NF1. The purpose of this report is to discuss the study of a patient with classical features of both NF-I and NF-II, emphasizing the need for surveillance regarding sporadic mutations seen in NF I AND NF II genes, as well as genetic mosaicism to be kept in mind when diagnosing such patients.
View Article and Find Full Text PDFFront Genet
October 2024
Department of Otolaryngology-Head and Neck Surgery, Qilu Hospital of Shandong University, Qingdao, China.
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) belongs to a subtype of Chronic rhinosinusitis which is a heterogeneous inflammatory condition. It has been reported that mitophagy may provide a new therapeutic option for CRSwNP.
Methods: The GSE136825 (training dataset) and GSE179265 (validation dataset) were scoured from the Gene Expression Omnibus database.
Zhongguo Zhen Jiu
October 2024
Department of Acupuncture-Moxibustion and Rehabilitation, First Affiliated Hospital of Anhui University of CM, Hefei 230031.
Based on Chinese medicine classics, combined with clinical experience and modern research findings, Professor deepens the analysis on the etiology and pathogenesis of neuropathic tinnitus, and has summarized the TCM elements of this disease, including " and blood stagnation" and " (spirit) hidden and orifices closed". The multiple therapies are used in combination, such as acupuncture, electroacupuncture, warm needling, borneol-moxibustion and herbal medication. The different acupoints are combined according to individuals, especially the application of Tinggong (SI 19) and Yamen (GV 15).
View Article and Find Full Text PDFImmunology
December 2024
Meniere Disease Neuroscience Research Program, Faculty of Medicine and Health, School of Medical Sciences, The Kolling Institute, University of Sydney, Sydney, New South Wales, Australia.
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