Recent advancements in pharmaceutical and gene therapy research have led to the development of novel compounds and delivery systems that target critical areas of unmet medical needs, including drug-resistant bacterial infections, cancer, and genetic diseases. This Patent Highlight reviews the key findings from three recent patents that describe innovations in tricyclic quinolone compounds and adeno-associated virus (AAV) vectors for gene editing. These innovations demonstrate significant progress in the treatment of antibiotic-resistant bacterial infections, BCL6-dependent cancers, and the efficient delivery of CRISPR-based gene editing tools.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11403721 | PMC |
http://dx.doi.org/10.1021/acsmedchemlett.4c00405 | DOI Listing |
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