AI Article Synopsis

  • Idiopathic granulomatous mastitis (IGM) is a rare, benign inflammatory breast disease that mainly affects premenopausal women with a history of breastfeeding, first described in 1972.
  • A 38-year-old African American woman was diagnosed with a painful right breast mass after finding it during a self-exam; imaging revealed a suspicious mass prompting further biopsy.
  • The case emphasizes that IGM can resemble breast cancer, necessitating more research to improve understanding and avoid unnecessary treatments.

Article Abstract

Introduction: Idiopathic granulomatous mastitis (IGM), also known as nonpuerperal mastitis or granulomatous lobular mastitis, is a rare, benign, chronic inflammatory breast disease first characterized in 1972. IGM is characterized by sterile noncaseating lobulocentric granulomatous inflammation, usually affecting parous premenopausal women with a history of lactation.

Case Presentation: We present a 38-year-old African American woman presenting to our continuity clinic complaining of a painful right breast mass discovered during a self-breast examination. An initial right breast ultrasound demonstrated an area of concern with asymmetry, architectural distortion, and a questionable mass correlating to a 5.1 cm hypoechoic mass at the 12:30 position. Additionally, a mammogram showed a suspicious, indeterminate, large hypoechoic region or mass with angular margins measuring 5.1 x 1.7 x 3.7 cm with slight internal vascularity. An ultrasound-guided stereotactic biopsy revealed extensive mixed inflammatory and focal granulomatous lobular mastitis.

Conclusion: Idiopathic granulomatous mastitis is a rare disorder that often mimics breast malignancies and infectious processes. This case highlights the need for further research on IGM pathogenesis to prevent unnecessary life-altering therapeutic procedures and bring awareness to the medical community.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11404587PMC
http://dx.doi.org/10.36518/2689-0216.1684DOI Listing

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