AI Article Synopsis
- An efficient method for creating 1,1-dichloroalkenes from organoboron compounds is reported, using manganese(III) triacetate and trichloroethylene (TCE) as key reagents.
- * The reaction is versatile, accommodating different organoboron compounds and functional groups, yielding moderate to good results.
- * Interestingly, the process is also successful with manganese(II) acetate and can be adapted to synthesize other chloroalkenes, including 1,1,2-trichloroalkenes.
Article Abstract
Herein, we report an efficient method for the synthesis of 1,1-dichloroalkenes from organoboron compounds. This reaction proceeds in the presence of manganese(III) triacetate using trichloroethylene (TCE) as the vinylation reagent. This reaction can tolerate various types of organoboron compounds and various functional groups. The yields are moderate to good. Surprisingly, this transformation could even be achieved in the presence of manganese(II) acetate. Furthermore, this synthetic strategy could be applied to the synthesis of 1,1,2-trichloro-, 1-chloro-, and 2-chloroalkenes.
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| http://dx.doi.org/10.1021/acs.joc.4c00635 | DOI Listing |
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