Histopathological changes in testicular lesions in cats.

J Feline Med Surg

Department of Veterinary Clinical Sciences, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Hong Kong SAR, China.

Published: September 2024

AI Article Synopsis

  • - This study examined testicular lesions in cats in Hong Kong from 2018 to 2024, focusing on both neoplastic (tumor-related) and non-neoplastic (non-tumor-related) findings.
  • - Out of 26 testis samples from 18 cats, non-neoplastic lesions were more common, especially inflammation and conditions like cryptorchidism, while neoplastic lesions were found in three older cats, including Sertoli cell tumor, leiomyoma, and fibrosarcoma.
  • - The research highlights that non-neoplastic lesions are prevalent and identifies new instances of leiomyoma and fibrosarcoma in cats’ testes, suggesting the need for awareness about these possible conditions.

Article Abstract

Objectives: The aim of this retrospective study was to describe the neoplastic and non-neoplastic lesions seen on histopathological examination of cat testes in Hong Kong between 2018 and 2024.

Methods: A total of 26 single or dual testes samples were collected from 18 cats by veterinarians at 14 veterinary clinics and submitted for histopathological examination. Laboratory records, including signalment, lesion location, age, breed and histopathological findings, were reviewed for each cat.

Results: Neoplastic testicular lesions were seen in three older cats (median age 8.5 years; range 3-17) compared with 18 non-neoplastic lesions in 15 cats (median age 1 year; range 0.5-3). The most common non-neoplastic lesions included inflammation (in the testes, epididymis, tunics and ductus deferens), cryptorchidism, and one case each of polyorchidism and epididymal cyst formation. Two of the testes with inflammation were identified on immunohistochemical staining as feline coronavirus-infected and one pair of testes was associated with the presence of extracellular Gram-negative bacteria at the lesion site. Three different neoplastic lesions were identified, one each of Sertoli cell tumour, leiomyoma and fibrosarcoma.

Conclusions And Relevance: Non-neoplastic testicular lesions were most common, including inflammation, cryptorchidism, polyorchidism and epididymal cysts. To our knowledge, leiomyoma and fibrosarcoma have not been reported in cat testes before and represent important differential diagnoses for testicular lesions.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11418622PMC
http://dx.doi.org/10.1177/1098612X241264124DOI Listing

Publication Analysis

Top Keywords

testicular lesions
16
non-neoplastic lesions
12
lesions
8
lesions cats
8
histopathological examination
8
cat testes
8
cats median
8
median age
8
polyorchidism epididymal
8
testes
6

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!