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"Just Be Relentless," Lessons Learned from In-Hospital Addiction Consult Service Implementation.
J Gen Intern Med
January 2025
Section of Addiction Medicine in Division of General Internal Medicine, Department of Medicine, Oregon Health & Science University, Portland, OR, USA.
Background: Hospitalization is a "reachable" moment to engage people in addiction care. Addiction consult services (ACSs) have been shown to improve outcomes for hospitalized patients with substance use disorders (SUDs). Despite this, most hospital systems do not provide hospital-based addiction care or have an ACS.
View Article and Find Full Text PDFLessons Learned from the Implementation of the Wake County, North Carolina EMS Medication for Opioid Use Disorder Program.
Prehosp Emerg Care
January 2025
Wake County Emergency Medical Services, 331 S. McDowell St, Raleigh, NC 27601.
Objectives: Buprenorphine has recently emerged as a prehospital treatment for opioid use disorder. Limited data exist regarding the implementation of prehospital buprenorphine programs. Our objective was to describe the development, deployment, lessons learned, and ongoing evolution of the Wake County EMS buprenorphine program using data from the first year following implementation.
View Article and Find Full Text PDFBackground: Amyloid PET imaging is an established diagnostic tool for Alzheimer's disease, but its successful integration into clinical practice requires a comprehensive understanding of its impact on patients and the healthcare system. In 2022, the coverage with evidence development (CED) ENABLE study has been approved by the German Federal Joint Committee (trial registration: DRKS00030839). The study is scheduled to start in early 2024.
View Article and Find Full Text PDFBackground: A lesson of the recent progress in Alzheimer's Disease therapy is that biomarker-driven trials will be crucial to demonstrating efficacy in the clinic. Many studies have demonstrated the potential predictive power of fluid and imaging biomarkers in guiding patient selection and continued progress of precision medicine approaches will demand development of multi-dimensional biomarker arrays. However, correlations between candidate biomarkers change non-linearly with time, requiring methodologies to align biomarkers across a common disease timescale (time from amyloid positivity; TFAP).
View Article and Find Full Text PDFPublic Health.
Alzheimers Dement
December 2024
Erasmus MC University Medical Center, Rotterdam, Zuid Holland, Netherlands.
Background: The expected seasonal recurrence of (new variants of) COVID-19 and the emergence of other airborne infectious diseases underscore the need for a sustainable healthcare preparedness strategy. It is particularly essential to ensure equitable access to healthcare for individuals with chronic diseases, including dementia and Parkinson's Disease. Moreover, it is vital to provide clinicians and researchers in the neurodegenerative disease fields with resources and infrastructure to ensure continuity of their work, even during a pandemic.
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