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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11403204 | PMC |
| http://dx.doi.org/10.1093/jacamr/dlae137 | DOI Listing |
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QMAC-dRAST for direct testing of antibiotic susceptibility in positive blood-culture broth: a comparison with the BD Phoenix system and the disc diffusion method.
JAC Antimicrob Resist
October 2024
Laboratoire de Bactériologie-Hygiène Hospitalière, Centre Hospitalier Universitaire Grenoble Alpes, F-38000, Grenoble, France.
QMAC-dRAST for the direct testing of antibiotic susceptibility for Enterobacterales in positive blood-culture broth: a comparison of the performances with the MicroScan system and direct disc diffusion testing methods.
J Antimicrob Chemother
March 2023
AP-HP, Henri Mondor Hospital, Department of Prevention, Diagnosis and Treatment of Infections, Paris-Est-Créteil University, Créteil, France.
Objectives: To evaluate the performances of the QMAC-dRAST GN (Gram-negative) kit for rapid antimicrobial sensitivity testing (AST) and two other methods, directly on positive blood-culture broth (PBCB), by comparison with a reference method: the MicroScan method based on broth microdilution on colonies isolated on PBCB subculture.
Methods: In total, 156 samples were collected prospectively from blood cultures positive for a Gram-negative rod. Each sample was tested with four AST techniques: (i) the QMAC dRAST GN kit, (ii) the disc diffusion (DD) method, (iii) the MicroScan method applied directly to PBCB; and (iv) MicroScan with isolates from PBCB subculture, as a reference.
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