Calciphylaxis in a 30-Year-Old Woman With Alcoholic Cirrhosis: A Case Report.

Cureus

Department of Radiology and Nuclear Medicine, Jackson Memorial Hospital, Miami, USA.

Published: September 2024

AI Article Synopsis

  • Calciphylaxis is a rare but serious condition affecting patients with end-stage renal disease (ESRD), leading to poor outcomes due to calcium and phosphorus buildup in blood vessels and soft tissues.
  • Diagnosis can be made through skin biopsies or imaging techniques like X-ray and bone scintigraphy, emphasizing the significance of these methods.
  • This report discusses a case of a 30-year-old woman with calciphylaxis, pointing out the effectiveness of bone scintigraphy for diagnosis and the crucial role of organ transplant for adequate treatment.

Article Abstract

A diagnosis of calciphylaxis is rare amongst the vulnerable population of patients with end-stage renal disease (ESRD); however, it has poor outcomes when it does present. With ineffective clearance due to reduced kidney function, calcium and phosphorus accumulate and deposit in the intimal layer of blood vessels and other soft tissues throughout the body. It can be proven using biopsy of skin lesions characteristic of the disease or with less invasive methods including X-ray and bone scintigraphy. Calciphylaxis is typically seen in middle-aged patients who have undergone prolonged dialysis treatment and has a devastating prognosis unless the patient can obtain a renal transplant. In this report, we present a case of a 30-year-old female patient with calciphylaxis and highlight the value of bone scintigraphy for diagnosis, while noting the importance of organ transplant for proper treatment.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11404531PMC
http://dx.doi.org/10.7759/cureus.69527DOI Listing

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