Purpose: Less than 50% of people with HIV (PWH) in the United States are retained in care, a key step along the HIV care continuum. We examined the impact of geographic access to care on retention in care for urban and rural PWH.
Methods: We used Medicaid claims and clinician data (Medicaid Analytic eXtract and MAX Provider Characteristics, 2009-2012) for 13 Southern states plus the District of Columbia. We calculated drive time from the enrollees' ZIP Code Tabulation Area to their usual source of care. We used generalized estimating equations to examine the association between drive time to care >30 min (versus ≤30 min) and retention in care, overall and stratified by rurality. In sensitivity analysis, we examined the definition of retention in care, states included in the analysis, and enrollee- and care-related characteristics.
Findings: The sample included 49,596 PWH. Overall, the association between drive time >30 min and retention was significant, but small (adjusted odds ratio [aOR] 1.01, 95% confidence interval [CI] 1.00, 1.01) and was not significant in urban areas; however, the significance and direction of the association differed in sensitivity analysis. In rural areas, driving >30 min to care was associated with 7% higher odds of retention in care (aOR 1.07, 95% CI 1.05, 1.08) and this association remained significant and positive in nearly all sensitivity analyses.
Conclusions: For PWH in rural areas, greater drive time is consistently associated with greater retention in care. Disentangling the mechanisms of this relationship is a future research priority.
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http://dx.doi.org/10.1111/jrh.12877 | DOI Listing |
Eur J Orthop Surg Traumatol
January 2025
Department of Orthopaedic Surgery, University of California San Diego, 200 West Arbor Drive MC 8894, San Diego, CA, 92103, USA.
Purpose: While treatment modalities for Maisonneuve fractures involving the proximal third of the fibula are established, no studies to date have reported outcomes associated with syndesmotic-only fixation of middle third fibular shaft fractures. The purpose of this study was to evaluate outcomes associated with syndesmotic-only fixation in the treatment of Maisonneuve fractures involving the middle third of the fibula.
Methods: A retrospective review was conducted on 257 cases of syndesmotic ankle instability with associated fibular fractures at a level 1 trauma center between 2013 and 2023.
Clin Drug Investig
January 2025
Department of Medicine, Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Perelman School of Medicine, 423 Guardian Drive, Philadelphia, PA, 19104, USA.
Purpose: The REDUCE-IT randomized trial demonstrated a cardiovascular benefit of icosapent ethyl (IPE) but also raised potential safety signals for atrial fibrillation (AF) and serious bleeding. We aimed to evaluate the real-world safety of IPE versus mixed omega-3 polyunsaturated fatty acid (OM-3) formulations.
Methods: This retrospective active comparator new-user cohort study compared rates of new-onset AF and major bleeding (MB) among adult new users of IPE versus OM-3 in 2020-2024 US Veterans Affairs data.
Small
January 2025
Nanotechnology and Bio-Engineering Research Group, Atlantic Technological University, ATU Sligo, Ash Lane, Sligo, F91 YW50, Ireland.
The rising demand for efficient energy storage in flexible electronics is driving the search for materials that are well-suited for the fabrication of these devices. Layered Double Hydroxides (LDHs) stand out as a remarkable material with a layered structure that embodies exceptional electrochemical properties. In this study, both double-shelled and single-shelled NiFe-Layered Double Hydroxide (LDH) particles are prepared using spindle-shaped MIL-101(Fe) as the template.
View Article and Find Full Text PDFSensors (Basel)
January 2025
Department of Computer Science, College of Charleston, Charleston, SC 29424, USA.
As modern vehicles continue to evolve, advanced technologies are integrated to enhance the driving experience. A key enabler of this advancement is the Controller Area Network (CAN) bus, which facilitates seamless communication between vehicle components. Despite its widespread adoption, the CAN bus was not designed with security as a priority, making it vulnerable to various attacks.
View Article and Find Full Text PDFSensors (Basel)
January 2025
Seamless Trans-X Lab (STL), School of Integrated Technology, Yonsei University, Incheon 21983, Republic of Korea.
In the domain of autonomous driving, trajectory prediction plays a pivotal role in ensuring the safety and reliability of autonomous systems, especially when navigating complex environments. Unfortunately, trajectory prediction suffers from uncertainty problems due to the randomness inherent in the driving environment, but uncertainty quantification in trajectory prediction is not widely addressed, and most studies rely on deep ensembles methods. This study presents a novel uncertainty-aware multimodal trajectory prediction (UAMTP) model that quantifies aleatoric and epistemic uncertainties through a single forward inference.
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