Epigenetic editing alleviates Angelman syndrome phenotype in mice by unsilencing paternal Ube3a.

Yajing Liu Sensen Lou Jinhui Li Yuanhua Liu Shisheng Huang Yu Wei Jikai Liu Ruimin Lv Junjie Tang Zhixin Shen Yidi Sun Xingxu Huang Zhiqi Xiong Hui Yang Changyang Zhou

Cell Discov

Institute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Research Center for Brain Science and Brain-Inspired Intelligence, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.

Published: September 2024

Download full-text PDF	Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11405779	PMC
http://dx.doi.org/10.1038/s41421-024-00727-3	DOI Listing

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