The effect of pomegranate supplementation on symptom severity and quality of life in women with premenstrual syndrome: A randomised controlled trial.

J Affect Disord

Sakarya University, Faculty of Health Sciences, Department of Nursing, Esentepe Campus, 54187 Serdivan, Sakarya, Türkiye. Electronic address:

Published: January 2025

Background: The aim of this study was to find out how well pomegranate use affects quality of life and PMS symptoms.

Methods: This randomised controlled trial (Clinical trial number: NCT06201702) was conducted in a city in the western region of Turkey, reaching women with PMS through social media announcements. Data were collected between 2 January 2024 and 15 May 2024. In the study of 60 participants (intervention group: 30, control group: 30), the intervention group was given pomegranate exrat supplementation for 2 cycles, while the control group did not receive any intervention. The research data were collected through a descriptive information, Premenstrual Syndrome Scale and World Health Organisation Quality of Life Scale. IBM SPSS Version 23 software was used for data analysis. Chi-square test, paired sample t-test and independent sample t-test were used. P-value <.05 was considered statistically significant.

Results: When the intervention and control groups were compared in terms of premenstrual syndrome scores, a statistically significant difference was found and it was observed that symptoms decreased significantly in the intervention group after the intervention (p < .05). However, no statistically significant change was observed in the control group (p > .05). When the quality of life scores after the intervention were evaluated, it was seen that the social quality of life of the intervention group was higher than the control group (p < .05).

Conclusions: This study shows that pomegranate may be a potential natural solution, especially in reducing PMS symptoms, and may also be effective in improving social quality of life.

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http://dx.doi.org/10.1016/j.jad.2024.09.079DOI Listing

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