Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Landscape of Global Pediatric Oncology Publications: A Cross-Sectional Analysis.
JCO Glob Oncol
January 2025
Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN.
Purpose: The academic field of global pediatric oncology is expanding as cancer becomes increasingly recognized as a global health priority for children and adolescents. Here, we aimed to explore the representation of authors, the geographic distribution of research, and the research approaches being used in global pediatric oncology.
Methods: Articles published in () and on the topic of global pediatric oncology were analyzed.
Results From First-in-Human Phase I Study of a Novel CD19-1XX Chimeric Antigen Receptor With Calibrated Signaling in Large B-Cell Lymphoma.
J Clin Oncol
January 2025
Center for Cell Engineering, Sloan Kettering Institute, New York, NY.
Purpose: We designed a CD19-targeted chimeric antigen receptor (CAR) comprising a calibrated signaling module, termed 1XX, that differs from that of conventional CD28/CD3ζ and 4-1BB/CD3ζ CARs. Preclinical data demonstrated that 1XX CARs generated potent effector function without undermining T-cell persistence. We hypothesized that 1XX CAR T cells may be effective at low doses and elicit minimal toxicities.
View Article and Find Full Text PDFLonger recreational screen time contributes to the risk of age-related macular degeneration: a UK Biobank cohort study and two-sample Mendelian randomisation.
J Glob Health
January 2025
Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: Recreational screen time (RST) has been found to be associated with cognitive decline and neurodegenerative diseases. However, the association between RST and age-related macular degeneration (AMD), an ocular neurodegenerative disease, is still unclear. We aimed to elucidate the association between RST and AMD.
View Article and Find Full Text PDFA framework for managing infectious diseases in rural areas in low- and middle-income countries in the face of climate change-East Africa as a case study.
PLOS Glob Public Health
January 2025
Global Health Program, Smithsonian Conservation Biology Institute, Washington, DC, United States of America.
Climate change is having unprecedented impacts on human health, including increasing infectious disease risk. Despite this, health systems across the world are currently not prepared for novel disease scenarios anticipated with climate change. While the need for health systems to develop climate change adaptation strategies has been stressed in the past, there is no clear consensus on how this can be achieved, especially in rural areas in low- and middle-income countries that experience high disease burdens and climate change impacts simultaneously.
View Article and Find Full Text PDFPrevalence of soil-transmitted helminths infection and associated risk factors among residents of Jigjiga town, Somali region, Eastern Ethiopia.
PLoS One
January 2025
School of Medicine, Institute of Health Science, Jigjiga University, Jigjiga, Ethiopia.
Background: One of the tropical illnesses that is often overlooked is soil-transmitted helminths, or STHs. In tropical and subtropical nations, where poor sanitation and contaminated water sources are common, they mostly impact the most vulnerable populations.
Objective: The aim of this study was to ascertain the prevalence of STHs and related risk factors among the people living in Jigjiga town, Somali region, Eastern Ethiopia.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!