AI Article Synopsis

  • A bacterium can grow in the human stomach, causing chronic inflammation, peptic ulcers, and cancer, and this study focuses on its prevalence among Nunavik's Inuit population using data from 2004 and 2017.
  • The study found high rates of colonization (70.9%) and associated issues like gastritis (11.2%) and peptic ulcers (2.4%), with few cases of gastric cancer reported.
  • Factors influencing higher colonization included the number of people in a household and age, while drinking municipal or natural water and lower alcohol consumption were linked to reduced colonization rates.

Article Abstract

is a bacterium that may colonise and proliferate in human stomachs, leading invariably to chronic inflammation and, to a lesser extent, to peptic ulcers and cancer. The main objective of this study is to describe the epidemiology surrounding in Nunavik's Inuit population using the 2004 and 2017 Health Surveys. Estimated prevalences were 70.9% for bacterial colonisation using a stool antigens test (SAT), 72.5% for anti- antibodies, 12.7% for faecal occult blood in participants aged ≥ 50 and respectively of 28.4%, 11.2% and 2.4% for a prior diagnosis of colonisation, gastritis and peptic ulcer in the medical charts, with under five cases of gastric cancer reported. Variables associated with higher SAT+ prevalence were the number of household members (prevalence ratio [PR] = 1.03) and age (quadratic relationship), whereas mainly drinking municipal (PR = 0.84) and natural water (PR = 0.72) compared to bottled water, and increasing alcohol consumption (PR = 0.96) were associated with reduced prevalence. Despite current regional guidelines targeting high risk individuals in the context of high prevalence, Nunavik's health authorities must remain vigilant by following gastric cancer incidence and the rapid evolution of guidelines, while considering local realities.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11407425PMC
http://dx.doi.org/10.1080/22423982.2024.2398864DOI Listing

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