species are renowned for their ability to produce a wide range of secondary metabolites with medicinal properties. In this study, compounds were isolated from sp. Z-16, of which compound is a new benzophenone derivative named methyl 2-(2,6-dihydroxy-4-methylbenzoyl)-4,5-dihydroxy-3-methoxybenzoate. The chemical structure of was determined through comprehensive spectroscopic analysis, including 1D, 2D NMR (HMBC, HSQC) and HRESIMS. In addition, six other known compounds () were isolated and identified from sp. T-5-1. The antimicrobial activity tests demonstrated that compound was moderately active against with a MIC value of 125 μg/mL, while compound showed a MIC value of 62.5 μg/mL against .
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