Colonoscopic Resolution of Melanosis Coli After Cessation of Senna Laxative Use.

Int Med Case Rep J

Department of Gastroenterology, Sanai Hospital, Morioka, Iwate, Japan.

Published: September 2024

AI Article Synopsis

  • Melanosis coli is a condition that can occur from using stimulant laxatives, such as senna, to relieve constipation.
  • An 81-year-old female who had taken senna laxatives for 5 years was diagnosed with melanosis coli through a colonoscopy.
  • After stopping the laxative for 7 months, a follow-up colonoscopy showed that her melanosis coli had completely resolved.

Article Abstract

Melanosis coli occurs with the administration of stimulant laxatives for the relief of constipation. However, the duration of macroscopic improvement of melanosis coli after discontinuation of anthracene laxatives is not well understood. We describe the case of an 81-year-old female diagnosed with melanosis coli via colonoscopy who had been taking senna laxatives for 5 years. Seven months after cessation of senna laxatives, colonoscopy showed no melanosis coli in the colon. This impressive report describes the observation of melanosis coli with colonoscopy; 7 months after the withdrawal of senna stimulant laxatives, melanosis coli resolved.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11402352PMC
http://dx.doi.org/10.2147/IMCRJ.S475869DOI Listing

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