AI Article Synopsis
- Poroid neoplasms (PN) are diverse tumors that originate from sweat glands, and their classification and identifying features can be difficult.
- A study conducted at the Niamey National Hospital from February 2020 to February 2024 found 13 cases of benign poroid neoplasms, mostly classic poromas, with a majority being misdiagnosed as malignant before surgery.
- The results indicate that these tumors often have apocrine ductal features and tend to occur in younger patients and non-palmoplantar areas, challenging traditional understandings of their characteristics.
Article Abstract
Introduction: Poroid neoplasms (PN) are a heterogeneous group of tumors deriving from sweat glands and folliculo-sebaceous units. Their histological classification and clinical features are challenging. Our aim was to report clinicopathological features of poroid neoplasms.
Methods: It is a retrospective study including all cases of poroid neoplasms registered at our Pathology laboratory of Niamey National Hospital (February 2020-February 2024).
Results: We registered 13 cases of benign poroid neoplasms: 10 classic poromas (CP) (76.9%), 2 poroid hidradenomas (PH) (15.4%) and 1 dermal duct tumor (DDT) (7.7%). Nine cases (69.2%) had preoperative clinical diagnosis of malignancy. The mean age was 41.1 years (range of 12-70 years) with a slight female predominance. Only 4/13 cases (30.8%) had classical palmoplantar locations. The tumors mean size was 3.7 cm (range of 0.4-8 cm). Clear cells were present in 7 cases (53.8%), apocrine ductal differentiation (mixed or pure) in 6 cases (46.2%), keratin horns in 2 cases (15.4%), squamous eddies in 6 cases (46.2%), melanin pigments in 1 case (7.7%) and sebaceous differentiation in 2 cases (15.4%).
Conclusions: Unlike what is classically reported, our study shows that apocrine ductal differentiation, younger age and non-palmoplantar locations are common in poroid neoplasms.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11402061 | PMC |
| http://dx.doi.org/10.1177/2632010X241281460 | DOI Listing |
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