AI Article Synopsis
- Chlorfenapyr is an insecticide that disrupts the energy production process in cells, leading to severe poisoning effects in humans.
- Symptoms of chlorfenapyr poisoning include excessive sweating, dangerously high body temperature, muscle breakdown, and delayed neurological issues that may worsen over time.
- Physicians need to be cautious when treating chlorfenapyr poisoning, as patients can appear stable initially but may experience life-threatening symptoms later; the paper discusses three cases to highlight these concerns.
Article Abstract
Chlorfenapyr, an arylpyrrole-based insecticide, disrupts mitochondrial oxidative phosphorylation to deprive the target organism of energy. Chlorfenapyr poisoning in humans causes distinct clinical signs such as hyperhidrosis, malignant hyperthermia, rhabdomyolysis, and delayed neurological symptoms that worsen over time and can be fatal. When treating acute chlorfenapyr poisoning, physicians must consider the latent period and not assume that a patient is safe after an initial response to treatment. It is important to take measures before sudden, fatal symptoms appear. This paper presents three cases of chlorfenapyr poisoning as a warning for physicians to understand its clinical course and treatment.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11402109 | PMC |
| http://dx.doi.org/10.1016/j.toxrep.2024.101703 | DOI Listing |
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