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| http://dx.doi.org/10.1016/j.jseint.2024.05.008 | DOI Listing |
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Protective effect of compound K against podocyte injury in chronic kidney disease by maintaining mitochondrial homeostasis.
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January 2025
The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, People's Republic of China.
Chronic kidney disease (CKD) stands as a formidable global health challenge, often advancing to end-stage renal disease (ESRD) with devastating morbidity and mortality. At the central of this progression lies podocyte injury, a critical determinant of glomerular dysfunction. Compound K (CK), a bioactive metabolite derived from ginsenoside, has emerged as a compelling candidate for nephroprotective therapy.
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This case study describes a successful nutrition social marketing program in Afghanistan. By building up the domestic soy industry and supply chain, while creating consumer demand for high-protein soy products to combat malnutrition, the campaign rebalanced the market dynamics for this relatively unknown locally grown crop. The campaign included technical assistance to the soy industry and retailers, a consumer media campaign, and community outreach via influencers, government agencies, and events.
View Article and Find Full Text PDFA Phaeocystis bloom in the northern Beibu Gulf reflects nutrient-driven shifts in dominant phytoplankton taxa.
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CAS Key Laboratory of Marine Ecology and Environmental Sciences, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China.
Large-scale Phaeocystis globosa blooms in the Beibu Gulf have adversely affected marine ecosystems and the functioning of a nuclear power plant. To understand the formation mechanisms for such large-scale blooms, we examined the P. globosa bloom dynamics in the northern Beibu Gulf from September 2015 to March 2016 in association with changes in phytoplankton community and environmental factors.
View Article and Find Full Text PDFInhibition of SGLT2 protects podocytes in diabetic kidney disease by rebalancing mitochondria-associated endoplasmic reticulum membranes.
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Division of Nephrology, Department of Medicine, The Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, Guangdong, 519000, China.
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View Article and Find Full Text PDFStructural insights into carboxylic-acid based DES across H-bond donor ratios: impact of CL&Pol refinement.
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Donostia International Physics Center (DIPC), Manuel Lardizabal Ibilbidea, 4, Donostia, 20018, Euskadi, Spain.
Deep eutectic solvents (DES) are of significant interest due to their eco-friendly nature and vast applications. Carboxylic-acid-based choline chloride (ChCl) DES are notable for their roles in electrochemical, drug delivery, and biomass processing applications, with efficiency influenced by the ChCl : carboxylic acid ratio. Understanding these mechanisms requires detailed knowledge of their structure.
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