Although publication in scholarly peer-reviewed journals remains the gold standard for communication of findings in the life sciences, the gold has been debased in the digital age by various impurities, including (a) reviewer fatigue, (b) fraud, paper mills, and the perils of artificial intelligence, (c) predatory journals, (d) the ongoing use of journal impact factor as a proxy for individual article quality, and (e) salami-slicing and other unethical practices. In this article, I present a detailed overview of these problems, as well as solutions proposed and implemented to counter them. Finally, I suggest that these are all symptomatic of a wider problem, namely the culture of 'publish or perish' and ongoing issues with how researcher performance is evaluated for grant, hiring, and promotion decisions. Only by working towards a global shift in the way scientists view the purpose of publication can we finally remove the impurities and refine the gold.
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In Situ Expression of Yak in Mammary Glands as a Treatment for Bovine -Induced Mastitis in Mice.
Vet Sci
October 2024
College of Animal Science and Veterinary Medicine, Southwest Minzu University, Chengdu 610041, China.
Since the development of dairy farming, bovine mastitis has been a problem plaguing the whole industry, which has led to a decrease in milk production, a reduction in dairy product quality, and an increase in costs. The use of antibiotics to treat mastitis can cause a series of problems, which can bring a series of harm to the animal itself, such as the development of bacterial resistance and dramatic changes in the gut flora. However, the in vivo and in vitro antibacterial activity of yak Interleukin-22 (IL-22) and its application in mastitis caused by have not been reported.
View Article and Find Full Text PDFFive problems plaguing publishing in the life sciences-and one common cause.
FEBS Lett
September 2024
FEBS Letters Editorial Office, Cambridge, UK.
Although publication in scholarly peer-reviewed journals remains the gold standard for communication of findings in the life sciences, the gold has been debased in the digital age by various impurities, including (a) reviewer fatigue, (b) fraud, paper mills, and the perils of artificial intelligence, (c) predatory journals, (d) the ongoing use of journal impact factor as a proxy for individual article quality, and (e) salami-slicing and other unethical practices. In this article, I present a detailed overview of these problems, as well as solutions proposed and implemented to counter them. Finally, I suggest that these are all symptomatic of a wider problem, namely the culture of 'publish or perish' and ongoing issues with how researcher performance is evaluated for grant, hiring, and promotion decisions.
View Article and Find Full Text PDFThe application of antibiotics in the poultry and veterinary sectors is very common practice in India. Owing to the seriousness of antimicrobial resistance (AMR), the present study has illustrated the overall scenario of AMR in the poultry and veterinary sectors in India through an in-depth scoping review and key informant interview (KII). In the poultry sector, most of the studies reviewed have reported resistant bacteria isolated from chicken meat, eggs, cloacal swabs, and fecal samples, and only a few have reported the presence of resistant bacteria in and around the environment of poultry farms.
View Article and Find Full Text PDFBioactivation of Konjac Glucomannan Films by Tannic Acid and Gluconolactone Addition.
ACS Appl Mater Interfaces
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Department of Biomaterials Technology, Faculty of Mechanical Engineering and Ship Technology, Gdańsk University of Technology, Gabriela Narutowicza 11/12, 80-229 Gdańsk, Poland.
Wound healing is a dynamic process that requires an optimal extracellular environment, as well as an accurate synchronization between various cell types. Over the past few years, great efforts have been devoted to developing novel approaches for treating and managing burn injuries, sepsis, and chronic or accidental skin injuries. Multifunctional smart-polymer-based dressings represent a promising approach to support natural healing and address several problems plaguing partially healed injuries, including severe inflammation, scarring, and wound infection.
View Article and Find Full Text PDFSynthesis and Performance Study of Self-Degradable Gel Plugging Agents Suitable for Medium- and Low-Temperature Reservoirs.
ACS Omega
August 2024
School of Chemical and Environmental Engineering, Yangtze University, Jingzhou 434023, China.
Aiming at the problems of current similar hydrogel plugging agents, such as poor breaking performance, nonspontaneous degradation, and reservoir pollution which have been plaguing their application in temporary plugging operations, this study has synthesized a cross-linking agent for hydrogels with dimethylaminoethyl acrylate and dibromo--xylene as raw materials. With Fourier transform infrared, H nuclear magnetic resonance, and thermogravimetric analyses as representations of the structure and thermal stability of the cross-linking agent, a set of self-degrading hydrogel systems has been developed with the cross-linking agent as the core so as to make evaluations on the temperature resistance, plugging performance, and core damage performance of the hydrogel and conduct a study on its gelation kinetics. The research results show that the cross-linking agent shows good thermal stability.
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