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Manifestations of Endocrine Disease in the Lower Extremities: Beyond the Diabetic Foot. | LitMetric

Manifestations of Endocrine Disease in the Lower Extremities: Beyond the Diabetic Foot.

Int J Low Extrem Wounds

Diabetes Centre, Second Department of Internal Medicine, University Hospital of Alexandroupolis, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.

Published: September 2024

AI Article Synopsis

  • The review discusses various endocrine diseases and their effects on the lower extremities, excluding diabetic foot.
  • Conditions such as acromegaly, Addison's disease, and thyroid disorders can manifest with distinct clinical signs in this area.
  • Early diagnosis through clinical suspicion and treating the endocrine issue typically leads to improvement in symptoms related to the lower extremities.

Article Abstract

The aim of this narrative review was to discuss manifestations of endocrine disease other than diabetic foot in the lower extremities. Acromegaly, Addison's disease, Cushing's syndrome, hypo- and hyperthyroidism, hypo- and hyperparathyroidism, autoimmune polyglandular syndrome, hypopituitarism, and glucagonoma are among the endocrine diseases that may present with clinical manifestations in the lower extremities. Clinical signs vary depending on the underlying condition. Clinical suspicion is necessary for early diagnosis. Treatment of the underlying endocrine disease usually results in improvement of lower-extremity manifestations.

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Source
http://dx.doi.org/10.1177/15347346241284059DOI Listing

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