AI Article Synopsis

  • The study aimed to compare the effectiveness of multidisciplinary coordinated care (CC) against traditional care (TC) for children with anterior uveitis, focusing on patient outcomes from 2013 to 2022.
  • Results showed that CC led to significantly better disease control, quicker initiation of biologic treatments, and lower corticosteroid use compared to TC, along with fewer clinic visits.
  • The study concluded that multidisciplinary care improved patient outcomes but noted limitations like variations in cohort start times and unclear referral criteria for CC.

Article Abstract

Objective: We evaluated the impact of an Ophthalmology/Rheumatology multidisciplinary clinic for patients with anterior uveitis by comparing outcomes between those who received traditional care (TC) versus coordinated care (CC).

Methods: We conducted a retrospective cohort study of children with anterior uveitis from a pediatric tertiary care center between 2013 and 2022. Standard descriptive statistics were used; survival analyses explored differences in cohort disease activity and biologic disease-modifying antirheumatic drug (DMARD) treatment. Steroid treatment by cohort was compared using generalized estimating equation model with Poisson distribution and log link. Complications were compared using logistic regression. Number of visits in each cohort were assessed using Poisson generalized estimating equation model adjusted for complications.

Results: We studied 215 patients with anterior uveitis; 66% were female, 53% had juvenile idiopathic arthritis, and 23% were idiopathic, with a median age at diagnosis of 8 years old (interquartile range 5-12). CC was associated with a 60% higher hazard of reaching disease control (hazard ratio 1.6; P < 0.01) when controlling for time since diagnosis and anterior chamber cell counts at the beginning of disease activity. CC was associated with starting biologic DMARDs earlier than TC (P < 0.01). Compared with the group who received TC, the group who received CC had a 96% lower rate of glucocorticoid reception per appointment within the first year (P < 0.01). The visit rate was 64% lower for the group who received CC when controlling for total complications per patient.

Conclusion: Patients who received multidisciplinary care had better outcomes than patients who received TC. Limitations include different cohort start times and absence of defined criteria for CC referral.

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Source
http://dx.doi.org/10.1002/acr.25433DOI Listing

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