Magnetic Resonance Imaging (MRI) plays a pivotal role in modern clinical practice, providing detailed anatomical visualization with exceptional spatial resolution and soft tissue contrast. Dynamic MRI, aiming to capture both spatial and temporal characteristics, faces challenges related to prolonged acquisition times and susceptibility to motion artifacts. Balancing spatial and temporal resolutions becomes crucial in real-world clinical scenarios. In the realm of dynamic MRI reconstruction, while Convolutional Recurrent Neural Networks (CRNNs) struggle with long-range dependencies, CRNNs require extensive iterations, impacting efficiency. Transformers, known for their effectiveness in high-dimensional imaging, are underexplored in dynamic MRI reconstruction. Additionally, prevailing algorithms fall short of achieving superior results in demanding generative reconstructions at high acceleration rates. This research proposes a novel approach for dynamic MRI reconstruction, named CRNN-Refined Spatiotemporal Transformer Network (CST-Net). The spatiotemporal Transformer initiates reconstruction, modeling temporal and spatial correlations, followed by refinement using the CRNN. This integration mitigates inaccuracies caused by damaged frames and reduces CRNN iterations, enhancing computational efficiency without compromising reconstruction quality. Our study compares the performance of the proposed CST-Net at 6 × and 12 × undersampling rates, showcasing its superiority over existing algorithms. Particularly, in challenging 25× generative reconstructions, the CST-Net outperforms current methods. The comparison includes experiments under both radial and Cartesian undersampling patterns. In conclusion, CST-Net successfully addresses the limitations inherent in existing generative reconstruction algorithms, thereby paving the way for further exploration and optimization of Transformer-based approaches in dynamic MRI reconstruction. Code and Datasets can be available: https://github.com/XWangBin/CST-Net.
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http://dx.doi.org/10.1016/j.compbiomed.2024.109133 | DOI Listing |
Proc Natl Acad Sci U S A
January 2025
Computational Radiology Laboratory, Boston Children's Hospital, Boston, MA 02115.
This study presents the construction of a comprehensive spatiotemporal atlas of white matter tracts in the fetal brain for every gestational week between 23 and 36 wk using diffusion MRI (dMRI). Our research leverages data collected from fetal MRI scans, capturing the dynamic changes in the brain's architecture and microstructure during this critical period. The atlas includes 60 distinct white matter tracts, including commissural, projection, and association fibers.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Neurosurgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Background: Glioblastoma is characterized by neovascularization and diffuse infiltration into the adjacent tissue. T2*-based dynamic susceptibility contrast (DSC) MR perfusion images provide useful measurements of the biomarkers associated with tumor perfusion. This study aimed to distinguish infiltrating tumors from vasogenic edema in glioblastomas using DSC-MR perfusion images.
View Article and Find Full Text PDFEur Heart J Cardiovasc Imaging
January 2025
Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.
Background: Cardiac magnetic resonance (CMR) is essential for diagnosing cardiomyopathy, serving as the gold standard for assessing heart chamber volumes and tissue characterization. Hemodynamic forces (HDF) analysis, a novel approach using standard cine CMR images, estimates energy exchange between the left ventricular (LV) wall and blood. While prior research has focused on peak or mean longitudinal HDF values, this study aims to investigate whether unsupervised clustering of HDF curves can identify clinically significant patterns and stratify cardiovascular risk in non-ischemic LV cardiomyopathy (NILVC).
View Article and Find Full Text PDFElife
January 2025
Department of Psychology, Queens University, Kingston, Canada.
Movie-watching is a central aspect of our lives and an important paradigm for understanding the brain mechanisms behind cognition as it occurs in daily life. Contemporary views of ongoing thought argue that the ability to make sense of events in the 'here and now' depend on the neural processing of incoming sensory information by auditory and visual cortex, which are kept in check by systems in association cortex. However, we currently lack an understanding of how patterns of ongoing thoughts map onto the different brain systems when we watch a film, partly because methods of sampling experience disrupt the dynamics of brain activity and the experience of movie-watching.
View Article and Find Full Text PDFCureus
December 2024
Neurology, Hassan II University Hospital, Fez, MAR.
Hirayama disease, also known as non-progressive juvenile spinal muscular atrophy of the upper limbs, brachial monomelic amyotrophy, or benign focal atrophy, affects the C7 D1 myotomes; an electromyogram (EMG) shows neurogenic damage in the C7-C8-T1 territories. It causes weakness and amyotrophy of the distal upper limb. Although it usually occurs on one side only, bilateral symmetric cases of Hirayama disease have occasionally been described.
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