Unveiling absent inferor vena cava in young patients: Case reports and clinical insights.

Int J Surg Case Rep

Division of Vascular and Endovascular Surgery, Department of Surgery, Shohada-Tajrish Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:

Published: October 2024

AI Article Synopsis

  • Inferior vena cava agenesis (IVCA) is a rare condition that accounts for about 5% of deep venous thrombosis (DVT) cases and can lead to significant complications if not properly diagnosed.
  • The article presents two case studies of young males diagnosed with absent inferior vena cava, one treated with Heparin and Rivaroxaban and the other with warfarin and compression therapy, both showing symptom resolution.
  • Early detection of AIVC is crucial in young patients with unexplained DVT, as it can guide appropriate long-term management strategies to prevent recurrent issues and chronic complications.

Article Abstract

Introduction: Inferior vena cava agenesis (IVCA), a rare congenital anomaly, contributes to approximately 5 % of deep venous thrombosis (DVT) cases lacking other risk factors. It can lead to chronic venous insufficiency and DVT when collateral circulation is insufficient, presenting diagnostic challenges due to its rarity.

Case Presentation: We present two cases of Absent IVC (AIVC) in young males. Case 1: a 22-year-old developed bilateral lower limb DVT post-appendectomy. Imaging revealed AIVC with azygos continuation. Treatment included Heparin and Rivaroxaban, achieving symptom resolution. Case 2: a 41-year-old with recurrent DVT and chronic venous insufficiency was diagnosed with AIVC via venography. Managed with warfarin and compression therapy, his symptoms stabilized.

Clinical Discussion: These cases underscore the importance of recognizing AIVC in young patients presenting with unexplained DVT. Diagnosis often requires advanced imaging techniques like CT venography. Management typically involves long-term anticoagulation and compression therapy to mitigate the risk of recurrence and chronic venous complications.

Conclusion: Early identification of AIVC in young adults presenting with recurrent DVT is essential for appropriate management and prevention of long-term complications.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11417193PMC
http://dx.doi.org/10.1016/j.ijscr.2024.110258DOI Listing

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