Management of biliary complications after LDLT.

Updates Surg

Master in HPB Surgery (Henri Bismuth Hepatobiliary Institute, France), European Inter-University Diploma in HPB Oncology, Fellowship in Hepatobiliary Surgery and Liver Transplantation (Hopital Paul Brousse, France), Director, Liver Transplantation and Hepatobiliary Surgery, Medanta Institute Of Liver Transplantation and Regenerative Medicine, Medanta - The Medicity, Gurgaon, Delhi NCR, 122001, India.

Published: September 2024

Biliary complications (BC) in the recipient continue to be an as yet, unresolved issue following living donor liver transplantation (LDLT). Bile leaks (BL) and biliary anastomotic strictures (BAS) are the most common BCs, with the latter contributing to close to 80%. With increasing expertise, endoscopic treatment with endoscopic retrograde cholangiography (ERC) [the first-line treatment] and percutaneous transhepatic cholangiography (PTC) with percutaneous transhepatic biliary drainage (PTBD) alone or in combination with ERC lead to successful management in a majority of these cases. However, prediction of difficulty of endoscopic success in biliary strictures, optimal duration of indwelling stents and their planned removal, management options in high-grade strictures (HGS) and the long-term outcome of patients requiring intervention for BC's are still unanswered questions in this setting. This review will try to summarise pertinent issues, novel insights and finally propose basic principles to be adhered to when dealing with the gamut of possible biliary complications after LDLT.

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Source
http://dx.doi.org/10.1007/s13304-024-01988-zDOI Listing

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