AI Article Synopsis
- Tetrahydroacridines show promise for medical applications and corrosion protection.
- New compounds were synthesized using Pfitzinger condensation and their structures confirmed with techniques like NMR, MS, and FT-IR.
- Computational studies and electrochemical methods were used to explore their properties, indicating potential use in pharmaceuticals and as corrosion inhibitors.
Article Abstract
Tetrahydroacridines arouse particular interest due to the potential possibilities of application in the medical field and protection against corrosion. -tetrahydroacridines were newly synthesized by Pfitzinger condensation of 5,5'-(ethane-1,2-diyl) diindoline-2,3-dione with several cyclanones. NMR, MS, and FT-IR were used to prove their molecular structure. In addition, a computer-aided study was performed for the lowest energy conformers of each structure, in vacuum conditions, at ground state using DFT models to assess their electronic properties. UV-Vis and voltammetric methods (cyclic voltammetry, differential pulse voltammetry, and rotating disk electrode voltammetry) were used to investigate their optical and electrochemical properties. The results obtained for these π-conjugated heteroaromatic compounds lead to the conclusion that they have real potential in applications in different fields such as pharmaceuticals and especially as corrosion inhibitors.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11396808 | PMC |
| http://dx.doi.org/10.3390/molecules29174082 | DOI Listing |
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