AI Article Synopsis

  • The widespread use of antibiotics in livestock raises global health concerns due to the emergence of antimicrobial-resistant bacteria affecting animals, humans, and the environment.
  • This study explores phenolic compounds as potential antibiotic alternatives, focusing on overcoming their low solubility and stability, while noting that advanced formulations may not be cost-effective.
  • Three phenolic compounds from wood processing were analyzed, showing promising antibacterial characteristics, particularly one effective against a major antibiotic-resistant pathogen, suggesting their potential as antimicrobial substitutes in livestock farming.

Article Abstract

The dispersion of antibiotics in livestock farming represents a health concern worldwide, contributing to the spread of antimicrobial-resistant bacteria through animals, the environment, and humans. Phenolic compounds could be alternatives to antibiotics, once drawbacks such as their low water solubility, bioavailability, and reduced stability are overcome. Although nano- or micro-sized formulations could counter these shortcomings, they do not represent cost-effective options. In this study, three phenolic compounds, obtained from wood-processing manufacturers, were characterized, revealing suitable features such as their antioxidant activity, size, and chemical and colloidal stability for in-field applications. The minimum inhibitory concentration (MIC) of these colloidal suspensions was measured against six bacterial strains isolated from livestock. These particles showed different inhibition behaviors: Colloidal chestnut was effective against one of the most threatening antibiotic-resistant pathogens, i.e., , but ineffective toward . Instead, colloidal pine showed a weak effect on but specificity toward . The present proof-of-concept points at colloidal polyphenols as valuable alternatives for antimicrobial substitutes in the livestock context.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11395071PMC
http://dx.doi.org/10.3390/ijms25179363DOI Listing

Publication Analysis

Top Keywords

phenolic compounds
8
colloidal
5
highly specific
4
specific polyphenolic
4
polyphenolic colloids
4
colloids alternatives
4
alternatives antimicrobials
4
livestock
4
antimicrobials livestock
4
livestock production
4

Similar Publications

Honey can benefit from non-thermal processing techniques such as high-pressure processing (HPP) to improve its quality and bioactivity. This study investigated the impact of HPP (600 MPa for 5, 10 and 15 min) on honey's quality, including the levels of hydroxymethylfurfural (HMF), antioxidant activity, total phenolic content (TPC) and phenolic profile. HPP treatment did not significantly affect HMF or TPC levels but led to selective changes in the phenolic profile.

View Article and Find Full Text PDF

Introduction: Saskatoon berries are grown in Canada and some northwestern states in the United States, and are notable for containing abundant antioxidant polyphenols, vitamins, metal elements, and fiber. To increase consumer interest in and accessibility to Saskatoon berries, some producers have begun to develop processes for refining Saskatoon berries into a powder with an extended shelf life that can be incorporated into a variety of value-added food products. To assess the desirability of this approach, this study sought to determine how the sensory attributes, consumer acceptability, and volatile and non-volatile composition of a plain, Greek-style frozen yogurt (PY) changed when fortified with 16% Saskatoon berry powder (SBP).

View Article and Find Full Text PDF

Given the abundance of beneficial properties and enzymes secreted by edible oyster mushrooms, their mycelium could serve as a starter for fermented foods to enhance their nutritional and bioactive quality. This study aimed to investigate the effects on the nutritional ingredients, antioxidant activity, and non-volatile metabolites during solid-state fermentation (SSF) of soybeans by mycelium. The results indicated that the contents of dietary fiber and starch in fermented soybeans decreased, while the amounts of protein and lipid increased after SSF ( < 0.

View Article and Find Full Text PDF

Kombucha is fermented and produced with a biofilm called a symbiotic culture of bacteria and yeast, which is drunk all over the world for its beneficial effects on human health and energy levels. The metagenomic study of kombucha frequently detected microorganisms in proteobacteria, firmicutes, and actinobacteria. And also, yeast and fungi are Ascomycota and Basidiomycota is present in green leaf and sugarcane juice fermented kombucha.

View Article and Find Full Text PDF

In the title compound, CHN·2CHNO, 4-nitro-phenol and 4,4'-bi-pyridine crystallized together in a 2:1 ratio in the space group 2/. There is a hydrogen-bonding inter-action between the nitro-gen atoms on the 4,4'-bi-pyridine mol-ecule and the hydrogen atom on the hydroxyl group on the 4-nitro-phenol, resulting in trimolecular units. This structure is a polymorph of a previously reported structure [Nayak & Pedireddi (2016 ▸).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!

A PHP Error was encountered

Severity: Notice

Message: fwrite(): Write of 34 bytes failed with errno=28 No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 272

Backtrace:

A PHP Error was encountered

Severity: Warning

Message: session_write_close(): Failed to write session data using user defined save handler. (session.save_path: /var/lib/php/sessions)

Filename: Unknown

Line Number: 0

Backtrace: