Postmortem Detection of "Clinically Undiagnosed" Diffuse Large B-Cell Lymphoma: Gross and Microscopic Findings.

Diagnostics (Basel)

Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Section of Legal Medicine, University of Messina, via Consolare Valeria 1, 98125 Messina, Italy.

Published: August 2024

AI Article Synopsis

  • Diffuse large B-cell lymphoma is the most common type of non-Hodgkin lymphoma in adults and is linked to certain health conditions, notably AIDS.
  • A case study discusses a 45-year-old man with AIDS who was diagnosed postmortem with this type of lymphoma.
  • The report includes images showing significant involvement of multiple body organs, which was confirmed by further histological analysis.

Article Abstract

Diffuse large B-cell lymphoma is considered the most found non-Hodgkin lymphoma in adults. Diffuse large B-cell lymphoma, which also occurs in sporadic forms, is associated with some pathological conditions, including human immunodeficiency virus infection, especially if it progresses to AIDS. The authors report the case of a 45-year-old man with AIDS in whom a postmortem diagnosis of diffuse large B-cell lymphoma was performed. The proposed images document extensive pluri-visceral involvement, already visible macroscopically, and subsequently confirmed through histological examination.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11394137PMC
http://dx.doi.org/10.3390/diagnostics14171901DOI Listing

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