A teaching course based on seemingly improbable curiosities could attract students’ interest in the magic of biochemical pathways and their evolution. [Image: see text]
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http://dx.doi.org/10.1038/s44319-024-00259-7 | DOI Listing |
Brain Res
December 2024
Programa de Pós-Graduação em Neurociências, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil; Departamento de Ciências Morfológicas, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Congenital Zika Syndrome (CZS) is a condition that arises when a neonate presents with abnormalities resulting from Zika virus infection during gestation. While microcephaly is a prominent feature of the syndrome, other forms of brain damage are also observed, often accompanied by significant neurological complications. It is therefore essential to investigate the long-term effects of CZS, with special attention to sex differences, particularly concerning hippocampal function, given its vulnerability to viral infections.
View Article and Find Full Text PDFDev Neurobiol
January 2025
Laboratory of Autism and Neurodevelopmental Research, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, Santa Catarina, Brazil.
Autism spectrum disorder (ASD) is characterized by deficits in communication, social interaction, and repetitive and stereotyped behaviors, with no specific drug therapy available. Studies have found that cannabidiol (CBD) can improve hyperactive and cognitive symptoms in children with ASD. However, little is known about the effect of CBD in combination with other medications, such as risperidone (RISP).
View Article and Find Full Text PDFNutrients
November 2024
Cardiometabolic Nutrition Group, Precision Nutrition Program, Research Institute on Food and Health Sciences IMDEA Food, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM), 28049 Madrid, Spain.
Unlabelled: Recent advances in machine learning technologies and omics methodologies are revolutionizing dietary assessment by integrating phenotypical, clinical, and metabolic biomarkers, which are crucial for personalized precision nutrition. This investigation aims to evaluate the feasibility and efficacy of artificial intelligence tools, particularly machine learning (ML) methods, in analyzing these biomarkers to characterize food and nutrient intake and to predict dietary patterns.
Methods: We analyzed data from 138 subjects from the European Dietary Deal project through comprehensive examinations, lifestyle questionnaires, and fasting blood samples.
Cent Nerv Syst Agents Med Chem
November 2024
Department of Pharmacology & Toxicology, School of Pharmaceutical Sciences, Delhi Pharmaceutical Sciences & Research University, New Delhi-17, India.
Background And Aim: This study aims to investigate the antidepressant properties of Hispidulin, a flavonoid present in Scutellaria barbata D. Don. The selection of Hispidulin stems from its notable inhibitory activity against Xanthine Oxidase (XO), a parameter in the pathophysiology of depression.
View Article and Find Full Text PDFJ Environ Sci Health A Tox Hazard Subst Environ Eng
December 2024
Centre for Marine and Environmental Studies (CESAM), Department of Biology, University of Aveiro, Aveiro, Portugal.
Caffeine (CAF) is widely detected in aquatic environments, serving as an indicator of anthropogenic contamination. Its high consumption, and persistence raise environmental concerns. This study was to evaluate the chronic effects in terms of growth rate, weight, behavior, and biochemical parameters of environmental concentrations of CAF on adult zebrafish.
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