AI Article Synopsis
- OCT and OCTA can help assess changes in the optic nerve structure for conditions like chronic primary angle-closure glaucoma (CPACG) and pituitary adenoma (PA).
- CPACG patients showed reduced retinal blood flow density and thinner retinal layers compared to PA patients, both factors being significant in diagnosis.
- The study concluded that both OCT and OCTA are effective in differentiating between early CPACG and early PA, even when visual field defects are similar.
Article Abstract
Optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) have the potential application in evaluating pathological structural change of the optic nerve. We aimed to evaluate the value of the OCT and OCTA parameters of the optic disk and macular in differentiating early chronic primary angle-closure glaucoma (CPACG) and early pituitary adenoma (PA) in case of mild visual field defects (the mean defect (MD) > 6 dB). The results showed that regarding OCTA parameters, CPACG patients had lower retinal blood flow density of most layers of the optic disk and macular than PA patients. Regarding OCT parameters, CPACG patients had thinner circumpapillary retinal nerve fiber layer (CP-RNFL) in all quadrants and average CP-RNFL, ganglion cell layer (GCL) and macular ganglion cell complex (GCC) in each quadrant of macular inner and outer rings, and inner plexus layer (IPL) of macular inner ring, superior-outer ring and temporal-outer ring than PA patients. The Z test indicated that OCTA parameters and OCT parameters had similar value in the diagnosis of disease. In conclusion, in the case of similar visual field damage, early CPACG patients have smaller blood flow density and thinner optic disk and macular than early PA. OCTA has similar performance to OCT in diagnosing CPACG and PA.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11399151 | PMC |
| http://dx.doi.org/10.1038/s41598-024-71103-0 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Use of Retinal Imaging Including Fundoscopy, OCT, and OCTA for Cardiovascular Risk Stratification and the Detection of Subclinical Atherosclerosis.
Curr Atheroscler Rep
January 2025
Department of Ophthalmology, NYU Langone Medical Center, New York, USA.
Purpose Of Review: Cardiovascular disease (CVD) is a leading cause of preventable morbidity and mortality globally, and retinal imaging modalities (old and new) are being explored as noninvasive tools to predict latent atherosclerosis and cardiovascular disease. This review focuses on the emerging promise of fundoscopy, optical coherence tomography (OCT), and optical coherence tomography angiography (OCTA) in CVD prognostication.
Recent Findings: High-quality studies have established the utility of vessel-based parameters and discrete conditions diagnosable via fundoscopy in subclinical atherosclerosis detection or CVD prediction.
Monitoring Progression in Hypertensive Patients with Dyslipidemia Using Optical Coherence Tomography Angiography: Can A.I. Be Improved?
J Clin Med
December 2024
Physio-Pathology and Immunology Department, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
: With the development of artificial intelligence (A.I.), the optical coherence tomography angiography (OCTA) analysis of progression in hypertensive retinopathy could be improved.
View Article and Find Full Text PDFObjectives: This study aimed to evaluate the correlations between optical coherence tomography angiography (OCTA), best corrected visual acuity (BCVA), and macular integrity assessment (MAIA) microperimetry (MP) in both a control group and patients with rhegmatogenous retinal detachment (RRD). Additionally, it assessed differences between the groups and examined whether the time from symptom onset to surgery influenced microvascular or functional changes in the RRD group.
Methods: A cross-sectional study was conducted involving 47 patients who had undergone successful RRD surgery with pars plana vitrectomy (PPV) and sulfur-hexafluoride (SF6) gas injection, with or without scleral buckling (SB), and a control group of 136 healthy eyes.
Compartmental analysis of retinal vascular parameters and thickness in myopic eyes using SS-OCTA.
Front Med (Lausanne)
December 2024
Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocular Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Article Synopsis
- The study examined how myopia affects the thickness and structure of retinal blood vessels using advanced imaging technology in 100 participants.
- The findings revealed that individuals with high myopia had significantly lower vessel density and thinner retinal layers, particularly noticeable in the superficial and nerve fiber layers.
- There was a noted correlation between certain ocular parameters, such as axial length to curvature radius ratio, and retinal thickness in non-high myopic eyes, while high myopic eyes showed less correlation in these aspects.
Purpose: To explore how serum diabetes autoantibodies are related to the development of early diabetic retinopathy in children with type 1 diabetes mellitus.
Methods: In this prospective and observational study, 62 patients with type 1 diabetes mellitus who had not yet developed clinical diabetic retinopathy were followed up for at least 5 years. Healthy volunteers aged 10 to 20 years were also included.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!