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Background And Objectives: Neurology residents serve as frontline teachers for junior trainees but often lack formal training in medical education. We developed a novel longitudinal curriculum to enhance the teaching skills and educational leadership of residents interested in pursuing careers as clinician-educators.

Methods And Curriculum Description: We developed and piloted a Neurology Clinician-Educator Program (NCEP) with the following goals: (1) improve resident satisfaction with opportunities to develop teaching skills, (2) improve resident satisfaction with opportunities to transition into a clinician-educator role after training, and (3) enhance resident teaching skills using evidence-based strategies.

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Socioemotional selectivity theory (SST) maintains that perceived constraints on time horizons motivate people to optimize emotionally meaningful experiences in the present, whereas expansive time horizons lead people to pursue goals that hold future utility. Theoretically, the prioritizing of goals about emotional meaning contributes to the relatively high levels of emotional well-being and mental health observed in older people. The present article provides an overview of SST and places it in historical context, noting the differences and similarities it shares with contemporaneous approaches.

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Agents seeking long-term access to the wisdom of the crowd reduce immediate decision-making accuracy.

Philos Trans R Soc Lond B Biol Sci

December 2024

Department of Statistics, School of Mathematics, University of Leeds, Leeds LS2 9JT, UK.

Living in groups offers social animals the significant advantage of accessing collective wisdom and enhanced information processing, enabling more accurate decisions related to foraging, navigation and habitat selection. Preserving group membership is crucial for sustaining access to collective wisdom, incentivizing animals to prioritize group cohesion. However, when individuals encounter divergent information about the quality of various options, this can create a conflict between pursuing immediate rewards and the maintenance of group membership to improve access to future pay-offs.

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Structure Revision of Halisphingosine A via Total Synthesis and Bioactivity Studies.

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Chemical Biology of Microbe-Host Interactions, Leibniz Institute for Natural Product Research and Infection Biology, Hans-Knöll Institute (Leibniz-HKI), Beutenbergstraße 11a, 07745, Jena, Germany.

Sphingoid bases are important bioactive lipids found in a variety of organisms, serving as the backbone of sphingolipids, which regulate essential physiological processes. Here we describe the total synthesis and structure revision of halisphingosine A, a sphingoid base initially isolated from marine sponges. To address inconsistencies in the NMR interpretation of this natural product, we developed a synthetic route involving a late-stage enantioselective Henry reaction that allows access to multiple stereoisomers of the proposed halisphingosine A core structure.

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