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What Do We Know About Speech-Language-Hearing Practice in Vocal Care for Transgender People? A Scoping Review.
J Voice
January 2025
School of Medicine - University of São Paulo (FM-USP), Speech Therapy, Physiotherapy and Occupational Therapy Department, São Paulo, São Paulo, Brazil. Electronic address:
Objective: To systematically assess the current state of speech-language-hearing (SLH) practices in health services addressing vocal care for transgender individuals, aiming to identify key themes and gaps in the existing body of knowledge.
Methods: This scoping review was based on the Joanna Briggs Institute manual and followed the recommendations of the Preferred Reporting Items for Systematic reviews and Meta-Analyses-Extension for Scoping Reviews. It was registered with the Open Science Framework Open Source 10.
HCTTI: High-Performance Heterogeneous Computing Toolkit for Tissue Image Stain Normalization.
J Imaging Inform Med
January 2025
Department of Pathology, Sinopharm Tongmei General Hospital, Datong, 037003, Shanxi, China.
Whole slide imaging (WSI) has transformed diagnostic medicine, particularly in the field of cancer diagnosis and treatment. The use of deep learning algorithms for predicting WSIs has opened up new avenues for advanced medical diagnostics. Additionally, stain normalization can reduce the color and intensity variations present in WSI from different hospitals.
View Article and Find Full Text PDFWhy and how should we simulate platform trials? Learnings from EU-PEARL.
BMC Med Res Methodol
January 2025
Center for Medical Data Science, Medical University of Vienna, Spitalgasse 23, Vienna, 1090, Austria.
Background: Platform trials are innovative clinical trials governed by a master protocol that allows for the evaluation of multiple investigational treatments that enter and leave the trial over time. Interest in platform trials has been steadily increasing over the last decade. Due to their highly adaptive nature, platform trials provide sufficient flexibility to customize important trial design aspects to the requirements of both the specific disease under investigation and the different stakeholders.
View Article and Find Full Text PDFThe UNICA Sleep HRV Analysis tool: an integrated open-source tool for heart rate variability analysis during sleep.
Physiol Meas
January 2025
Department of Electrical and Electronic Engineering (DIEE), University of Cagliari, Via Marengo, Cagliari, Sardegna, 09123, ITALY.
Heart rate variability (HRV) analysis during sleep plays a key role for understanding autonomic nervous system function and assessing cardiovascular health. The UNICA Sleep HRV analysis (UNICA-HRV) tool is a novel, open-source MATLAB tool designed to fill the gap in current HRV analysis tools. In particular, the integration of ECG and HRV data with hypnogram information, which illustrates the progression through the different sleep stages, ease the computation of HRV metrics in polysomnographic recordings.
View Article and Find Full Text PDFCXR-LLaVA: a multimodal large language model for interpreting chest X-ray images.
Eur Radiol
January 2025
Department of Radiology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Objective: This study aimed to develop an open-source multimodal large language model (CXR-LLaVA) for interpreting chest X-ray images (CXRs), leveraging recent advances in large language models (LLMs) to potentially replicate the image interpretation skills of human radiologists.
Materials And Methods: For training, we collected 592,580 publicly available CXRs, of which 374,881 had labels for certain radiographic abnormalities (Dataset 1) and 217,699 provided free-text radiology reports (Dataset 2). After pre-training a vision transformer with Dataset 1, we integrated it with an LLM influenced by the LLaVA network.
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