AI Article Synopsis
- γδT cells are a type of immune cell that has gained attention for their potential in cancer immunotherapy, despite being understudied.
- Recent research shows that γδT cells play important roles in tumor development, growth, and spread, revealing complex behaviors that vary depending on the tissue and context.
- The article explores how different subsets of γδT cells are regulated, how they interact with cancer and other immune cells, and the significance of these findings for cancer patients.
Article Abstract
γδT cells represent a group of immune cells that are understudied but whose utility has been recognized for cancer immunotherapy purposes. Recent studies have highlighted a critical role for these cells in tumor initiation, growth, and metastasis and revealed an increasingly complex biology of γδT cell subsets that is context and tissue specific. We discuss here how γδT cell subsets are regulated, their interaction with cancer and other immune cells, and the implications from these latest discoveries for people with cancer.
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| http://dx.doi.org/10.1016/j.ccell.2024.08.017 | DOI Listing |
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