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Publisher Correction: Development and characterization of a self-nano emulsifying drug delivery system (SNEDDS) for Ornidazole to improve solubility and oral bioavailability of BCS class II drugs.
Sci Rep
December 2024
Department of Industrial Chemistry, College of Science, Evangel University Akaeze, Ebonyi, Nigeria.
Correction: Ornidazole Inhibits the Angiogenesis and Migration Abilities of Non-small Cell Lung Cancer (NSCLC) via Downregulation of VEGFA/VEGFR2/NRP-1 and PI3K/AKT/mTOR Pathways.
Cell Biochem Biophys
September 2024
Department Of Medical Services And Techniques, Kahramanmaraş Health Services Vocational School, Pathology Laboratory Techniques Pr., Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.
The effectiveness of multivariate and univariate spectrophotometric techniques for the concurrent estimation of ornidazole and ciprofloxacin HCl in tablet formulation and spiked serum: estimating greenness and whiteness profile.
BMC Chem
January 2024
Analytical and Food Chemistry Dept., Faculty of Pharmacy, Aleppo University, Aleppo, Syria.
In this manuscript, the effectiveness of multivariate and univariate tools in conjunction with spectrophotometric techniques was evaluated for the concurrent analysis of ciprofloxacin (CI) and ornidazole (OR) in prepared mixtures, tablets, and human serum. The artificial neural network was chosen as the multivariate Technique. Bayesian regularization (trainbr) and Levenberg-Marquardt algorithms (trainlm), were constructed and trained using feed-forward back-propagation learning.
View Article and Find Full Text PDFThree new, UV spectrum filtration protocols for the synchronous quantification of ciprofloxacin HCl and ornidazole in the existence of ciprofloxacin-induced degradation compound.
Heliyon
December 2023
Analytical and Food Chemistry Dept., Faculty of Pharmacy, Aleppo University, Syria.
Three new spectrum filtration protocols have been developed and adapted to overcome some difficulties in dealing with highly overlapping triple drug mixtures by proposing new smart mathematical techniques that facilitate the resolution of the ternary mixture and the recovery of a filtrated zero-order spectrum (D spectrum) of each component without any overlapping from the accompanying components. The three established spectrophotometric protocols were conducted on the combination of ciprofloxacin hydrochloride and ornidazole as a green alternative to the usual chromatographic technique: the first protocol is ratio difference-isosbestic points coupled with ratio difference-areas under the curve (RD-ISO/RD-AUC); the second protocol is ratio difference-isosbestic points coupled with dual-wavelength equation (RD-ISO/DWE); and the third protocol is signal retrieval by zero-crossing point (SRZ). All three developed protocols have the power to recover a filtrated zero-order spectrum of each ornidazole and ciprofloxacin hydrochloride without any involvement from the ciprofloxacin-induced degradation substance through processing their spectral data either in the zero-order spectrum, ratio spectrum, or derivative spectrum.
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