The accumulation of SIRT4 in the nuclei of kidney cells drives kidney fibrosis, so blocking the movement of this protein could be a potential therapeutic strategy against fibrosis.
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| http://dx.doi.org/10.7554/eLife.102355 | DOI Listing |
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Lock out SIRT4.
Elife
September 2024
School of Biomedical Sciences, University of Hong Kong, Hong Kong, Hong Kong.
The accumulation of SIRT4 in the nuclei of kidney cells drives kidney fibrosis, so blocking the movement of this protein could be a potential therapeutic strategy against fibrosis.
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