AI Article Synopsis

  • The growth of health technologies has led to an increased focus on biobanks, which are essential for research and experimental therapies using human biological samples.
  • The concept of biobanks has evolved from informal collections to well-organized institutions, with imaging biobanks emerging as a new field that combines medical images and biomarkers for research purposes.
  • The integration of imaging biobanks with traditional biobanks is important for advancing medical research, necessitating a clear legal and ethical framework, especially in Europe and Italy.

Article Abstract

The extraordinary growth of health technologies has determined an increasing interest in biobanks that represent a unique wealth for research, experimentation, and validation of new therapies. "Human" biobanks are repositories of various types of human biological samples. Through years the paradigm has shifted from spontaneous collections of biological material all over the world to institutional, organized, and well-structured forms. Imaging biobanks represent a novel field and are defined by European Society of Radiology as: "organized databases of medical images, and associated imaging biomarkers shared among multiple researchers, linked to other biorepositories". Modern radiology and nuclear medicine can provide multiple imaging biomarkers, that express the phenotype related to certain diseases, especially in oncology. Imaging biobanks, not a mere catalogue of bioimages associated to clinical data, involve advanced computer technologies to implement the emergent field of radiomics and radiogenomics. Since Europe hosts most of the biobanks, juridical and ethical framework, with a specific referral to Italy, is analyzed. Linking imaging biobanks to traditional ones appears to be a crucial step that needs to be driven by medical imaging community under clear juridical and ethical guidelines.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11391398PMC
http://dx.doi.org/10.3389/fdgth.2024.1408619DOI Listing

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